Korres George, Kitsos Dimitrios K, Kaski Diego, Tsogka Anthi, Giannopoulos Sotirios, Giannopapas Vasileios, Sideris Giorgos, Tyrellis Giorgos, Voumvourakis Konstantine
2nd ENT Department, Attikon University Hospital, 124 62 Athens, Greece.
2nd Department of Neurology, Attikon University Hospital, 124 62 Athens, Greece.
Brain Sci. 2022 Jul 20;12(7):948. doi: 10.3390/brainsci12070948.
Clinical manifestations of COVID-19 include symptoms of vertigo and dizziness, which is rather unsurprising, since SARS-CoV-2 neurotropism may inflict a broad spectrum of neuropathic effects. The widespread nature of central and peripheral audiovestibular pathways suggests that there may be several probable pathophysiological mechanisms. The cytokine storm, CNS infiltration of the virus through ACE 2 receptors, and other systemic factors can be responsible for the significant number of COVID-19 patients reported to experience symptoms of vertigo and dizziness. In this paper, we present a systematic review of clinical studies reporting the detection of dizziness and vertigo as clinical manifestations of COVID-19 and discuss their etiopathogenesis.
新冠病毒病（COVID-19）的临床表现包括眩晕和头晕症状，这并不奇怪，因为严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的嗜神经性可能会造成广泛的神经病变效应。中枢和外周听觉前庭通路的广泛分布表明可能存在多种潜在的病理生理机制。细胞因子风暴、病毒通过血管紧张素转换酶2（ACE 2）受体对中枢神经系统的浸润以及其他全身因素，可能是导致大量报告称出现眩晕和头晕症状的COVID-19患者的原因。在本文中，我们对报告将头晕和眩晕检测为COVID-19临床表现的临床研究进行了系统综述，并讨论了它们的病因。
