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The other COVID-19 survivors: Timing, duration, and health impact of post-acute sequelae of SARS-CoV-2 infection.其他 COVID-19 幸存者:SARS-CoV-2 感染后急性后遗症的发生时间、持续时间和健康影响。
J Clin Nurs. 2024 Jan;33(1):76-88. doi: 10.1111/jocn.16541. Epub 2022 Sep 30.
2
Direct SARS-CoV-2 infection of the human inner ear may underlie COVID-19-associated audiovestibular dysfunction.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)直接感染人类内耳可能是新冠病毒疾病(COVID-19)相关的听觉前庭功能障碍的潜在原因。
Commun Med (Lond). 2021;1(1):44. doi: 10.1038/s43856-021-00044-w. Epub 2021 Oct 29.
3
Incidence and duration of self-reported hearing loss and tinnitus in a cohort of COVID-19 patients with sudden chemosensory loss: A STROBE observational study.突发性化学感觉丧失的 COVID-19 患者队列中自我报告的听力损失和耳鸣的发生率和持续时间:一项 STROBE 观察性研究。
Eur Ann Otorhinolaryngol Head Neck Dis. 2022 May;139(3):125-128. doi: 10.1016/j.anorl.2021.07.012. Epub 2021 Sep 30.
4
Revised meta-analysis and pooled estimate of audio-vestibular symptoms associated with COVID-19.与新型冠状病毒肺炎相关的听觉前庭症状的修订荟萃分析和合并估计值
Int J Audiol. 2022 Aug;61(8):705-709. doi: 10.1080/14992027.2021.1962552. Epub 2021 Aug 25.
5
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EClinicalMedicine. 2021 Aug;38:101019. doi: 10.1016/j.eclinm.2021.101019. Epub 2021 Jul 15.
6
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Angiogenesis. 2021 Nov;24(4):755-788. doi: 10.1007/s10456-021-09805-6. Epub 2021 Jun 28.
7
Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.新型冠状病毒肺炎非住院患者的新冠后综合征:一项纵向前瞻性队列研究
Lancet Reg Health Eur. 2021 Jul;6:100122. doi: 10.1016/j.lanepe.2021.100122. Epub 2021 May 18.
8
6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records.236379 例 COVID-19 幸存者的 6 个月神经和精神结局:使用电子健康记录的回顾性队列研究。
Lancet Psychiatry. 2021 May;8(5):416-427. doi: 10.1016/S2215-0366(21)00084-5. Epub 2021 Apr 6.
9
One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms.一年后:SARS-CoV-2、COVID-19 和听觉-前庭症状的更新系统评价。
Int J Audiol. 2021 Dec;60(12):935-945. doi: 10.1080/14992027.2021.1896793. Epub 2021 Mar 22.
10
Changes in Tinnitus Experiences During the COVID-19 Pandemic.2019年冠状病毒病大流行期间耳鸣体验的变化
Front Public Health. 2020 Nov 5;8:592878. doi: 10.3389/fpubh.2020.592878. eCollection 2020.

一组成人长期新冠患者的自我报告耳鸣及眩晕或头晕情况

Self-reported Tinnitus and Vertigo or Dizziness in a Cohort of Adult Long COVID Patients.

作者信息

Degen Chantal Vanessa, Mikuteit Marie, Niewolik Jacqueline, Schröder Dominik, Vahldiek Kai, Mücke Urs, Heinemann Stephanie, Müller Frank, Behrens Georg Martin Norbert, Klawonn Frank, Dopfer-Jablonka Alexandra, Steffens Sandra

机构信息

Department of Otorhinolaryngology, Hannover Medical School, Hanover, Germany.

Dean's Office-Curriculum Development, Hannover Medical School, Hanover, Germany.

出版信息

Front Neurol. 2022 Apr 25;13:884002. doi: 10.3389/fneur.2022.884002. eCollection 2022.

DOI:10.3389/fneur.2022.884002
PMID:35547372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9082801/
Abstract

Tinnitus, vertigo and dizziness are symptoms commonly reported among Long and Post COVID patients, however the severity of these symptoms has not been assessed in large trials. Therefore, in this study a large cohort of Long COVID patients was surveyed about the presence and severity of tinnitus and vertigo or dizziness symptoms. The online survey was completed by a German cohort of 1,082 adult Long COVID patients after a mean period of 43.2 weeks ± 23.4 weeks after infection. Eighty percent were not fully vaccinated (at least two vaccinations) at the time of their first COVID symptoms and 9.8% were hospitalized in the course of their acute SARS-CoV-2 infection. At the time of the survey, 60% of patients reported the presence of vertigo or dizziness with a mean severity of 4.6 ± 2.7 on a scale of 1 (least severe) to 10 (most severe) and 30% complained of tinnitus with a mean severity of 4.8 ± 3.0. Approximately one fifth of the participants with tinnitus and vertigo or dizziness, rated their symptoms to be severe. The data shown in this study confirms that tinnitus and vertigo or dizziness are common symptoms in Long COVID patients and demonstrates, that a compelling number of patients rate their symptoms as severe. The self-reported severity highlights the need for Long COVID clinics to address these symptoms effectively. We suggest a multidisciplinary diagnostic and therapeutic approach to prevent further morbidity and socioeconomic burden for Long COVID patients suffering from severe vertigo, dizziness or tinnitus.

摘要

耳鸣、眩晕和头晕是长期新冠患者和新冠康复后患者中常见报告的症状,然而这些症状的严重程度尚未在大型试验中得到评估。因此,在本研究中,对一大群长期新冠患者进行了关于耳鸣、眩晕或头晕症状的存在及严重程度的调查。这项在线调查由1082名德国成年长期新冠患者组成的队列完成,调查时间为感染后平均43.2周±23.4周。80%的患者在首次出现新冠症状时未完全接种疫苗(至少接种两剂),9.8%的患者在急性SARS-CoV-2感染过程中住院。在调查时,60%的患者报告存在眩晕或头晕,平均严重程度在1(最不严重)至10(最严重)的量表上为4.6±2.7,30%的患者抱怨有耳鸣,平均严重程度为4.8±3.0。耳鸣、眩晕或头晕的参与者中约五分之一将他们的症状评为严重。本研究中显示的数据证实,耳鸣、眩晕或头晕是长期新冠患者的常见症状,并表明相当数量的患者将他们的症状评为严重。自我报告的严重程度凸显了长期新冠诊所有效解决这些症状的必要性。我们建议采用多学科诊断和治疗方法,以防止患有严重眩晕、头晕或耳鸣的长期新冠患者出现进一步的发病情况和社会经济负担。