Kasuga Noriki, Kurita Yusuke, Tanida Emiko, Yagi Shin, Suzuki Ko, Hasegawa Sho, Sato Takamitsu, Hosono Kunihiro, Kato Shingo, Sekino Yusuke, Kobayashi Noritoshi, Endo Itaru, Kubota Kensuke, Nakajima Atsushi
Department of Gastroenterology and Hepatology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Department of Gastroenterology, Machida Municipal Hospital, Tokyo 194-0023, Japan.
Diagnostics (Basel). 2022 Jul 9;12(7):1667. doi: 10.3390/diagnostics12071667.
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful in diagnosing subepithelial lesions (SELs), and adequate tissue sampling is necessary to differentiate between benign and malignant diseases to determine therapeutic strategies. This study aimed to evaluate sampling adequacy and diagnostic performance of EUS-FNA for SELs with Franseen needles. This retrospective study enrolled 130 patients who underwent EUS-FNA with a 22-gauge needle for SELs from January 2010 to March 2021. We compared sampling adequacy and predictive factors influencing the sampling adequacy of EUS-FNA for SELs between Franseen and conventional needles. The sampling adequacy rates were 95.0% (38/40) with Franseen needles and 76.7% (69/90) with conventional needles (p = 0.011). The mean number of punctures with Franseen needles (2.80) was significantly less than that with conventional needles (3.42) (p < 0.001). In the multivariate analysis, the use of Franseen needles (p = 0.029; odds ratio [OR], 5.37; 95% confidence interval [CI], 1.18−23.36) was an independent factor influencing the sampling adequacy. Compared to conventional needles, the Franseen needle could play a vital role in accurately diagnosing SELs by yielding better sampling adequacy and reducing the number of passes.
内镜超声引导下细针穿刺活检（EUS-FNA）在诊断上皮下病变（SELs）方面很有用，充分的组织采样对于区分良性和恶性疾病以确定治疗策略是必要的。本研究旨在评估使用 Franseen 针进行 EUS-FNA 对 SELs 的采样充分性和诊断性能。这项回顾性研究纳入了 2010 年 1 月至 2021 年 3 月期间接受 EUS-FNA 检查的 130 例 SELs 患者，使用 22 号针。我们比较了 Franseen 针和传统针在 EUS-FNA 对 SELs 的采样充分性及影响采样充分性的预测因素。 Franseen 针的采样充分率为 95.0%（38/40），传统针为 76.7%（69/90）（p = 0.011）。 Franseen 针的平均穿刺次数（2.80）显著少于传统针（3.42）（p < 0.001）。在多变量分析中，使用 Franseen 针（p = 0.029；优势比[OR]，5.37；95%置信区间[CI]，1.18−23.36）是影响采样充分性的独立因素。与传统针相比， Franseen 针通过产生更好的采样充分性和减少穿刺次数，在准确诊断 SELs 中可发挥重要作用。
