Department of Biofibers and Biomaterials Science, Kyungpook National University, Daegu 41566, Korea.
Preclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea.
Int J Mol Sci. 2022 Jul 6;23(14):7511. doi: 10.3390/ijms23147511.
Silk is a naturally occurring material and has been widely used in biomedical and cosmetic applications owing to its unique properties, including blood compatibility, excellent cytocompatibility, and a low inflammatory response in the body. A natural silk nonwoven fabric with good mechanical properties was recently developed using the binding property of sericin. In this study, silk/rayon composite nonwoven fabrics were developed to increase productivity and decrease production costs, and the effect of the silk/rayon composition on the structure and properties of the fabric was examined. The crystalline structure of silk and rayon was maintained in the fabric. As the silk content increased, the porosity and moisture regain of the silk/rayon web and nonwoven fabric decreased. As the silk content increased, the maximum stress of the web and nonwoven fabric increased, and the elongation decreased. Furthermore, the silk/rayon web exhibited the highest values of maximum stress and elongation at ~200 °C. Regardless of the silk/rayon composition, all silk/rayon nonwoven fabrics showed good cytocompatibility. Thus, the silk/rayon fabric is a promising material for cosmetic and biomedical applications owing to its diverse properties and high cell viability.
丝绸是一种天然材料,由于其独特的性能,如血液相容性、优异的细胞相容性和在体内的低炎症反应,已被广泛应用于生物医学和化妆品领域。最近,利用丝胶的结合性能开发出了一种具有良好机械性能的天然丝无纺制品。在这项研究中,开发了丝绸/人造丝复合非织造布,以提高生产效率和降低生产成本,并研究了丝绸/人造丝组成对织物结构和性能的影响。织物中保持了丝绸和人造丝的结晶结构。随着丝绸含量的增加,丝绸/人造丝网眼和非织造布的孔隙率和回潮率降低。随着丝绸含量的增加,网眼和非织造布的最大应力增加,伸长率降低。此外,在约 200°C 时,丝绸/人造丝网眼的最大应力和伸长率最高。无论丝绸/人造丝的组成如何,所有的丝绸/人造丝非织造布都表现出良好的细胞相容性。因此,由于其多样的性能和高细胞活力,丝绸/人造丝织物有望用于化妆品和生物医学应用。