Choi Hyo Geun, Yoo Dae Myoung, Kim Yoo Hwan, Kwon Mi Jung, Kim Joo-Hee, Song Joon Ho, Kim Ji Hee
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea.
Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea.
J Pers Med. 2022 Jul 20;12(7):1183. doi: 10.3390/jpm12071183.
There is scarcity in the evidence addressing the indirect impact of the COVID-19 pandemic on the epidemiology of CVDs. In this study we aimed to examine possible changes in the incidence of CVDs in Korea during the COVID-19 pandemic. ICD-10 codes of six common CVDs (cerebral hemorrhage, cerebral infarction, myocardial infarction, ischemic heart disease, cardiac failure, and arrhythmia) were collected from clinical visits between January 2018 and March 2021 using the National Health Insurance service database, which stores data on all citizens of Korea (~50 million people). The number and distribution of monthly visits for CVDs were compared before and during the COVID-19 pandemic, and the differences were analyzed using the Mann-Whitney U test and Levene's test. Our data showed similar incidences of cerebral hemorrhage and ischemic heart disease, a lower incidence of cerebral infarction, and higher incidences of myocardial infarction, cardiac failure, and arrhythmia during COVID-19. Despite statistical differences, the changes in incidences were not considered meaningful. The monthly incidences also remained similar throughout the year, without seasonal variations, both before and during the COVID-19 outbreak. This study found no significant changes in the incidences or monthly variation in CVDs due to the COVID-19 pandemic in Korea.
关于新冠疫情对心血管疾病（CVDs）流行病学的间接影响，相关证据较为匮乏。在本研究中，我们旨在调查韩国在新冠疫情期间心血管疾病发病率可能发生的变化。我们利用韩国国民健康保险服务数据库收集了2018年1月至2021年3月期间临床就诊中六种常见心血管疾病（脑出血、脑梗死、心肌梗死、缺血性心脏病、心力衰竭和心律失常）的国际疾病分类第十版（ICD - 10）编码，该数据库存储了韩国所有公民（约5000万人）的数据。比较了新冠疫情之前和期间心血管疾病每月就诊的数量和分布情况，并使用曼 - 惠特尼U检验和莱文检验分析差异。我们的数据显示，在新冠疫情期间，脑出血和缺血性心脏病的发病率相似，脑梗死发病率较低，而心肌梗死、心力衰竭和心律失常的发病率较高。尽管存在统计学差异，但发病率的变化被认为没有实际意义。在新冠疫情爆发之前和期间，全年每月发病率也保持相似，没有季节性变化。本研究发现，韩国因新冠疫情导致的心血管疾病发病率或每月变化没有显著变化。
