双相情感障碍患者产后复发
Postpartum Relapse in Patients with Bipolar Disorder.
作者信息
Conejo-Galindo Javier, Sanz-Giancola Alejandro, Álvarez-Mon Miguel Ángel, Ortega Miguel Á, Gutiérrez-Rojas Luis, Lahera Guillermo
机构信息
Psychiatry Department, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Alcalamente, Mental Health Service, 28806 Alcalá de Henares, Spain.
出版信息
J Clin Med. 2022 Jul 8;11(14):3979. doi: 10.3390/jcm11143979.
UNLABELLED
Pregnancy and postpartum are vital times of greater vulnerability to suffer a decompensation of bipolar disorder (BD).
METHODS
A systematic literature search was performed on public electronic medical databases, following PRISMA guidelines. Studies were included if they reported postpartum relapse in patients diagnosed with BD according to Diagnosis Statistical Manual (DSM) or International Classification Disease (ICD) criteria.
RESULTS
Sixteen articles describing 6064 deliveries of 3977 women were included in the quantitative analyses. The overall risk of postpartum relapse was 36.77%. The methodology of the studies, the diagnostic criteria, the discrimination between BD type I and II, and the origin of the sample were very heterogeneous.
CONCLUSIONS
the rate of postpartum bipolar relapse is very high, as it is considered to be a critical period. It is especially important to detect decompensation in this period and to evaluate mood-stabilizing treatment, given the high risk of relapse concentrated in a short period.
未标注
怀孕和产后是双相情感障碍（BD）病情更易出现失代偿的关键时期。
方法
按照PRISMA指南，在公共电子医学数据库中进行了系统的文献检索。如果研究报告了根据《诊断统计手册》（DSM）或《国际疾病分类》（ICD）标准诊断为双相情感障碍的患者产后复发情况，则纳入研究。
结果
定量分析纳入了16篇描述3977名女性6064次分娩的文章。产后复发的总体风险为36.77%。研究方法、诊断标准、双相情感障碍I型和II型的区分以及样本来源差异很大。
结论
产后双相情感障碍复发率非常高，因为这被认为是一个关键时期。鉴于复发风险集中在短时间内，在这一时期检测病情失代偿并评估心境稳定剂治疗尤为重要。
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