• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型冠状病毒肺炎感染患者的心肌缺血:病理生理机制与心电图表现之间的关系

Myocardial Ischemia in Patients with COVID-19 Infection: Between Pathophysiological Mechanisms and Electrocardiographic Findings.

作者信息

Duca Ștefania Teodora, Chetran Adriana, Miftode Radu Ștefan, Mitu Ovidiu, Costache Alexandru Dan, Nicolae Ana, Iliescu-Halițchi Dan, Halițchi-Iliescu Codruța-Olimpiada, Mitu Florin, Costache Irina Iuliana

机构信息

Department of Internal Medicine I, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700145 Iasi, Romania.

Department of Cardiology, "St. Spiridon" Emergency County Hospital, 700111 Iasi, Romania.

出版信息

Life (Basel). 2022 Jul 8;12(7):1015. doi: 10.3390/life12071015.

DOI:10.3390/life12071015
PMID:35888103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9318430/
Abstract

Given the possible pathophysiological links between myocardial ischemia and SARS-CoV-2 infection, several studies have focused attention on acute coronary syndromes in order to improve patients' morbidity and mortality. Understanding the pathophysiological aspects of myocardial ischemia in patients infected with SARS-CoV-2 can open a broad perspective on the proper management for each patient. The electrocardiogram (ECG) remains the easiest assessment of cardiac involvement in COVID-19 patients, due to its non-invasive profile, accessibility, low cost, and lack of radiation. The ECG changes provide insight into the patient's prognosis, indicating either the worsening of an underlying cardiac illnesses or the acute direct injury by the virus. This indicates that the ECG is an important prognostic tool that can affect the outcome of COVID-19 patients, which important to correlate its aspects with the clinical characteristics and patient's medical history. The ECG changes in myocardial ischemia include a broad spectrum in patients with COVID-19 with different cases reported of ST-segment elevation, ST-segment depression, and T wave inversion, which are associated with severe COVID-19 disease.

摘要

鉴于心肌缺血与SARS-CoV-2感染之间可能存在的病理生理联系,一些研究将重点放在急性冠状动脉综合征上,以改善患者的发病率和死亡率。了解感染SARS-CoV-2患者的心肌缺血病理生理方面,可为每个患者的恰当管理提供广阔视角。心电图(ECG)因其非侵入性、可及性、低成本和无辐射,仍然是评估COVID-19患者心脏受累情况最简单的方法。心电图变化有助于了解患者的预后,提示潜在心脏疾病的恶化或病毒的急性直接损伤。这表明心电图是一种重要的预后工具,可影响COVID-19患者的结局,将其各方面与临床特征和患者病史相关联很重要。COVID-19患者心肌缺血的心电图变化范围广泛,报道了不同病例出现ST段抬高、ST段压低和T波倒置,这些与严重的COVID-19疾病相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/eb2406fe0eca/life-12-01015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/5fec9ec327bc/life-12-01015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/87d83e29a6ee/life-12-01015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/eef1ff0c600d/life-12-01015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/eb2406fe0eca/life-12-01015-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/5fec9ec327bc/life-12-01015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/87d83e29a6ee/life-12-01015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/eef1ff0c600d/life-12-01015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69de/9318430/eb2406fe0eca/life-12-01015-g004.jpg

相似文献

1
Myocardial Ischemia in Patients with COVID-19 Infection: Between Pathophysiological Mechanisms and Electrocardiographic Findings.新型冠状病毒肺炎感染患者的心肌缺血:病理生理机制与心电图表现之间的关系
Life (Basel). 2022 Jul 8;12(7):1015. doi: 10.3390/life12071015.
2
Prognostic value of the admission electrocardiogram in acute coronary syndromes.急性冠状动脉综合征入院心电图的预后价值
JAMA. 1999 Feb 24;281(8):707-13. doi: 10.1001/jama.281.8.707.
3
Electrocardiographic findings over time and their prognostic value in patients with COVID-19.COVID-19 患者的心电图随时间的变化及其预后价值。
Ann Palliat Med. 2021 Dec;10(12):12280-12290. doi: 10.21037/apm-21-3188.
4
Electrocardiographic left ventricular hypertrophy in patients with suspected acute cardiac ischemia--its influence on diagnosis, triage, and short-term prognosis: a multicenter study.疑似急性心肌缺血患者的心电图左心室肥厚——对诊断、分诊及短期预后的影响:一项多中心研究
J Gen Intern Med. 1994 Dec;9(12):666-73. doi: 10.1007/BF02599006.
5
Influence of presenting electrocardiographic findings on the treatment and outcomes of patients with non-ST-segment elevation myocardial infarction.呈现心电图结果对非 ST 段抬高型心肌梗死患者治疗和结局的影响。
Am J Cardiol. 2014 Jan 15;113(2):256-61. doi: 10.1016/j.amjcard.2013.09.009. Epub 2013 Oct 2.
6
T-Wave Abnormality as Electrocardiographic Signature of Myocardial Edema in Non-ST-Elevation Acute Coronary Syndromes.T 波异常作为非 ST 段抬高型急性冠状动脉综合征中心肌水肿的心电图特征。
J Am Heart Assoc. 2018 Jan 26;7(3):e007118. doi: 10.1161/JAHA.117.007118.
7
Prognostic value of admission electrocardiographic findings in non-ST-segment elevation myocardial infarction.非 ST 段抬高型心肌梗死患者入院时心电图检查结果的预后价值。
Clin Cardiol. 2020 Jun;43(6):574-580. doi: 10.1002/clc.23349. Epub 2020 Mar 3.
8
Early continuous ST segment monitoring in unstable angina: prognostic value additional to the clinical characteristics and the admission electrocardiogram.不稳定型心绞痛早期连续ST段监测:除临床特征和入院心电图外的预后价值
Heart. 1996 Mar;75(3):222-8. doi: 10.1136/hrt.75.3.222.
9
Electrocardiographic classification of acute coronary syndromes: a review by a committee of the International Society for Holter and Non-Invasive Electrocardiology.急性冠状动脉综合征的心电图分类:动态心电图与无创心电学会委员会的综述
J Electrocardiol. 2010 Mar-Apr;43(2):91-103. doi: 10.1016/j.jelectrocard.2009.07.009. Epub 2009 Nov 14.
10
Prognostic value of the admission electrocardiogram in patients with unstable angina/non-ST-segment elevation myocardial infarction treated with very early revascularization.入院心电图对接受极早期血运重建治疗的不稳定型心绞痛/非ST段抬高型心肌梗死患者的预后价值。
Am J Med. 2004 Aug 1;117(3):145-50. doi: 10.1016/j.amjmed.2004.02.034.

引用本文的文献

1
Integrating the Interleukins in the Biomarker Panel for the Diagnosis and Prognosis of Patients with Acute Coronary Syndromes: Unraveling a Multifaceted Conundrum.将白细胞介素纳入急性冠状动脉综合征患者诊断和预后生物标志物组合:破解一个多方面的难题。
Diagnostics (Basel). 2025 May 11;15(10):1211. doi: 10.3390/diagnostics15101211.
2
Perioperative Coronavirus Disease 2019 Infection and Its Impact on Postoperative Outcomes: Pulmonary Complications and Mortality Based on Korean National Health Insurance Data.2019冠状病毒病围手术期感染及其对术后结局的影响:基于韩国国民健康保险数据的肺部并发症和死亡率
J Pers Med. 2025 Apr 17;15(4):157. doi: 10.3390/jpm15040157.
3

本文引用的文献

1
Wellens' Syndrome from COVID-19 Infection Assessed by Enhanced Transthoracic Coronary Echo Doppler: A Case Report.经增强经胸冠状动脉回声多普勒评估的新型冠状病毒肺炎感染所致Wellens综合征:一例报告
Diagnostics (Basel). 2022 Mar 25;12(4):804. doi: 10.3390/diagnostics12040804.
2
Electrocardiographic Features of Patients with COVID-19: An Updated Review.新型冠状病毒肺炎患者的心电图特征:最新综述。
Card Electrophysiol Clin. 2022 Mar;14(1):63-70. doi: 10.1016/j.ccep.2021.10.006. Epub 2021 Oct 30.
3
Subclinical myocardial injury, coagulopathy, and inflammation in COVID-19: A meta-analysis of 41,013 hospitalized patients.
COVID-19 beyond the lungs: Unraveling its vascular impact and cardiovascular complications-mechanisms and therapeutic implications.
新冠病毒肺炎的肺外表现:揭示其对血管的影响及心血管并发症——机制与治疗意义
Sci Prog. 2025 Jan-Mar;108(1):368504251322069. doi: 10.1177/00368504251322069. Epub 2025 Mar 16.
4
Are Pre-Hospitalization ECG Abnormalities Associated With Increased Mortality in COVID-19 Patients? A Quantitative Systematic Literature Review.COVID-19 患者住院前心电图异常与死亡率增加有关吗?一项定量系统文献综述。
Ann Noninvasive Electrocardiol. 2024 Nov;29(6):e70016. doi: 10.1111/anec.70016.
5
Association of COVID-19 With Emergence of Comorbidities: A Hospital-Based Cohort Study.新型冠状病毒肺炎与合并症出现的关联:一项基于医院的队列研究。
Cureus. 2024 Aug 4;16(8):e66147. doi: 10.7759/cureus.66147. eCollection 2024 Aug.
6
Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases.新型冠状病毒肺炎患者的非侵入性动态心电图标志物:三例报告
Medicina (Kaunas). 2024 Apr 19;60(4):655. doi: 10.3390/medicina60040655.
7
A prospective cohort study on post COVID syndrome from a tertiary care centre in Sri Lanka.斯里兰卡一家三级保健中心关于新冠后综合征的前瞻性队列研究。
Sci Rep. 2023 Sep 20;13(1):15569. doi: 10.1038/s41598-023-42350-4.
8
Distinct Features of Vascular Diseases in COVID-19.新冠病毒病中血管疾病的独特特征
J Inflamm Res. 2023 Jul 6;16:2783-2800. doi: 10.2147/JIR.S417691. eCollection 2023.
9
Pathophysiological effects of SARS-CoV-2 infection on the cardiovascular system and its clinical manifestations-a mini review.新型冠状病毒2019感染对心血管系统的病理生理影响及其临床表现——一篇综述
Front Cardiovasc Med. 2023 May 16;10:1162837. doi: 10.3389/fcvm.2023.1162837. eCollection 2023.
10
The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic.COVID-19大流行两年期间ST段抬高型心肌梗死患者的概况及全因院内死亡动态
J Clin Med. 2023 Feb 12;12(4):1467. doi: 10.3390/jcm12041467.
新型冠状病毒肺炎中的亚临床心肌损伤、凝血病和炎症:对41013例住院患者的荟萃分析
Int J Cardiol Heart Vasc. 2022 Jun;40:100950. doi: 10.1016/j.ijcha.2021.100950. Epub 2022 Jan 4.
4
Electrocardiographic Predictors of Primary Ventricular Fibrillation and 30-Day Mortality in Patients Presenting with ST-Segment Elevation Myocardial Infarction.ST段抬高型心肌梗死患者原发性心室颤动和30天死亡率的心电图预测指标
J Clin Med. 2021 Dec 17;10(24):5933. doi: 10.3390/jcm10245933.
5
ECG pathology and its association with death in critically ill COVID-19 patients, a cohort study.危重症 COVID-19 患者心电图病理及其与死亡的关联:一项队列研究。
PLoS One. 2021 Dec 14;16(12):e0261315. doi: 10.1371/journal.pone.0261315. eCollection 2021.
6
Evolutionary de Winter pattern: from STEMI to de Winter ECG-a case report.进化型 de Winter 图形:从 STEMI 到 de Winter 心电图——1 例报告。
ESC Heart Fail. 2022 Feb;9(1):771-774. doi: 10.1002/ehf2.13711. Epub 2021 Nov 30.
7
The de Winter electrocardiographic pattern as an ST-elevation myocardial infarction equivalent in a young patient with COVID-19.
Emergencias. 2021 Dec;33(6):484-485.
8
Electrocardiographic abnormalities in COVID-19 patients visiting the emergency department: a multicenter retrospective study.在急诊科就诊的 COVID-19 患者的心电图异常:一项多中心回顾性研究。
BMC Emerg Med. 2021 Nov 19;21(1):141. doi: 10.1186/s12873-021-00539-8.
9
[A case of Wellens syndrome during the COVID-19 pandemic].[新冠疫情期间的一例Wellens综合征病例]
G Ital Cardiol (Rome). 2021 Nov;22(11):888-890. doi: 10.1714/3689.36745.
10
The Role of Endothelial Related Circulating Biomarkers in COVID-19. A Systematic Review and Meta-analysis.内皮相关循环生物标志物在 COVID-19 中的作用:系统评价和荟萃分析。
Curr Med Chem. 2022;29(21):3790-3805. doi: 10.2174/0929867328666211026124033.