Popa-Fotea Nicoleta-Monica, Grigore Iulia-Adelina, Calmac Lucian, Mihai Cosmin, Bataila Vlad, Ploscaru Vlad, Dragoescu Bogdan, Moldovan Horatiu, Busnatu Stefan-Sebastian, Panaitescu Eugenia, Iliuță Luminita, Scafa-Udriște Alexandru
Department of Cardio-Thoracic Pathology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Cardiology, Emergency Clinical Hospital, 014461 Bucharest, Romania.
J Clin Med. 2023 Feb 12;12(4):1467. doi: 10.3390/jcm12041467.
During the coronavirus pandemic 2019 (COVID-19), some studies showed differences in the profile of subjects presenting with acute coronary syndromes as well as in overall mortality due to the delay of presentation and other complications. The purpose of this study was to compare the profile and outcomes, with emphasis on all-cause in-hospital mortality, of ST-elevation myocardial infarction (STEMI) subjects presenting to the emergency department during the pandemic period compared with a control group from the previous year, 2019. The study enrolled 2011 STEMI cases, which were divided into two groups-pre-pandemic (2019-2020) and pandemic period (2020-2022). Hospital admissions for a STEMI diagnosis sharply decreased during the COVID-19 period by 30.26% during the first year and 25.4% in the second year. This trend was paralleled by a significant increase in all-cause in-hospital mortality: 11.5% in the pandemic period versus 8.1% in the previous year. There was a significant association between SARS-CoV-2 positivity and all-cause in-hospital mortality, but no correlation was found between COVID-19 diagnosis and the type of revascularization. However, the profile of subjects presenting with STEMI did not change over time during the pandemic; their demographic and comorbid characteristics remained similar.
在2019年冠状病毒大流行（COVID-19）期间，一些研究表明，因就诊延迟和其他并发症，出现急性冠状动脉综合征的患者情况以及总体死亡率存在差异。本研究的目的是比较大流行期间到急诊科就诊的ST段抬高型心肌梗死（STEMI）患者与2019年上一年的对照组在特征和结局方面的差异，重点关注全因住院死亡率。该研究纳入了2011例STEMI病例，分为两组——大流行前（2019 - 2020年）和大流行期间（2020 - 2022年）。在COVID - 19期间，STEMI诊断的住院人数在第一年急剧下降了30.26%，在第二年下降了25.4%。这一趋势伴随着全因住院死亡率的显著上升：大流行期间为11.5%，而上一年为8.1%。SARS-CoV-2阳性与全因住院死亡率之间存在显著关联，但未发现COVID-19诊断与血运重建类型之间存在相关性。然而，在大流行期间，出现STEMI的患者情况并未随时间变化；他们的人口统计学和合并症特征保持相似。
