Division of Plastic and Reconstructive Surgery, Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.
School of Medicine, Tzu Chi University, Hualien 970, Taiwan.
Medicina (Kaunas). 2022 Jun 24;58(7):846. doi: 10.3390/medicina58070846.
The neutralizing anti-interferon-γ autoantibody (nAIGA)-associated immunodeficiency is an emerging entity frequently associated with the nontuberculosis mycobacterium (NTM) infection and other opportunistic infections. We present a female patient with a mysterious periocular complex (MAC) infection, accompanied by sequential opportunistic infections including and herpes zoster infection. Her condition stabilized after long-term antimycobacterial treatment. Nevertheless, neutralizing anti-interferon-γ autoantibody was found in her serum, which was compatible with the scenario of adult-onset immunodeficiency.
中性抗干扰素-γ 自身抗体（nAIGA）相关免疫缺陷是一种新兴实体，常与非结核分枝杆菌（NTM）感染和其他机会性感染相关。我们报告了一位女性患者，她患有神秘的眶周复杂（MAC）感染，并伴有连续的机会性感染，包括和带状疱疹感染。她在长期抗分枝杆菌治疗后病情稳定。然而，在她的血清中发现了中性抗干扰素-γ 自身抗体，这与成人发病免疫缺陷的情况相符。
