Kanyala Estelle, Shuaib Yassir Adam, Schwarz Norbert Georg, Andres Sönke, Richter Elvira, Sawadogo Bernard, Sawadogo Mamadou, Germaine Minoungou, Lassina Ouattara, Poppert Sven, Frickmann Hagen
Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso BP 390, Burkina Faso.
College of Veterinary Medicine, Sudan University of Science and Technology, P.O. Box 204, Khartoum North 13321, Sudan.
Microorganisms. 2022 Jul 8;10(7):1378. doi: 10.3390/microorganisms10071378.
This cross-sectional study was conducted at the slaughterhouses/slabs of Oudalan and Ouagadougou in Burkina Faso, between August and September 2013. It aimed at determining the prevalence of bovine tuberculosis (bTB) suggestive lesions in slaughtered cattle carcasses and to identify and characterize the mycobacteria isolated from these lesions. A thorough postmortem examination was conducted on carcasses of a total of 2165 randomly selected cattle. The overall prevalence of bTB suggestive lesions was 2.7% (58/2165; 95% CI 2.1-3.5%). Due to the low number of positive samples, data were descriptively presented. The lesions were either observed localized in one or a few organs or generalized (i.e., miliary bTB) in 96.6% ( = 57) and 3.4% ( = 2), respectively. The identified mycobacteria were (44.4%, = 20), (8.9%, = 4), (6.7%, = 3), (4.4%, = 2), (2.2%, = 1), (2.2%, = 1), (2.2%, = 1), and unknown non-tuberculous mycobacteria (NTM) (11.1%, = 5). Moreover, eight mixed cultures with more than one species growing were also observed, of which three were and and three were and . In conclusion, is the predominant causative agent of mycobacterial infections in the study area. Our study has identified a base to broaden the epidemiological knowledge on zoonotic transmission of mycobacteria in Burkina Faso by future studies investigating further samples from humans and animals, including wild animals employing molecular techniques.
这项横断面研究于2013年8月至9月在布基纳法索的乌达兰和瓦加杜古的屠宰场进行。其目的是确定屠宰牛尸体中牛结核病（bTB）疑似病变的患病率，并鉴定和表征从这些病变中分离出的分枝杆菌。对总共2165头随机挑选的牛的尸体进行了全面的尸检。bTB疑似病变的总体患病率为2.7%（58/2165；95%置信区间2.1 - 3.5%）。由于阳性样本数量较少，数据采用描述性呈现。病变分别在96.6%（ = 57）和3.4%（ = 2）的病例中观察到局限于一个或几个器官或全身性（即粟粒性bTB）。鉴定出的分枝杆菌有结核分枝杆菌（44.4%， = 20）、牛分枝杆菌（8.9%， = 4）、非洲分枝杆菌（6.7%， = 3）、副结核分枝杆菌（4.4%， = 2）、堪萨斯分枝杆菌（2.2%， = 1）、胞内分枝杆菌（2.2%， = 1）、戈登分枝杆菌（2.2%， = 1）以及未知的非结核分枝杆菌（NTM）（11.1%， = 5）。此外，还观察到8种有不止一种分枝杆菌生长的混合培养物，其中3种是结核分枝杆菌和牛分枝杆菌，3种是结核分枝杆菌和非洲分枝杆菌。总之，结核分枝杆菌是研究区域内分枝杆菌感染的主要病原体。我们的研究确定了一个基础，未来通过采用分子技术对包括野生动物在内的人和动物的更多样本进行研究，以拓宽布基纳法索分枝杆菌人畜共患病传播的流行病学知识。
