United States Department of Agriculture, Infectious Bacterial Disease Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, IA, USA.
BMC Vet Res. 2013 May 8;9:100. doi: 10.1186/1746-6148-9-100.
Mycobacteria other than M. bovis may interfere with current bovine tuberculosis diagnostic tests resulting in false positive test results. As the prevalence of M. bovis decreases in the United States, interference from other mycobacteria play an increasingly important role in preventing the eradication of M. bovis. To identify mycobacteria other than M. bovis that may be interfering with current diagnostic tests, a retrospective study was performed to identify mycobacteria isolated from clinical tissues at the National Veterinary Services Laboratories between 1 January 2004 and 9 October 2011.
During the study period, 2,366 mycobacteria other than M. bovis were isolated from samples submitted for clinical diagnosis of M. bovis. Fifty-five mycobacterial species were isolated during this time period. In cattle, M. avium complex, M. fortuitum/fortuitum complex, M. smegmatis, M. kansasii, and M. terrae complex were the predominate species other than M. bovis isolated from tissues submitted for culture. Mycobacteria other than M. bovis isolated from deer were predominantly M. avium complex, M. terrae/terrae complex, and M. fortuitum/fortuitum complex.
These data provide information characterizing the species and relative prevalence of mycobacteria other than M. bovis that may interfere with current diagnostic tests.
除牛分枝杆菌以外的分枝杆菌可能会干扰当前的牛结核病诊断测试，导致假阳性测试结果。随着美国牛分枝杆菌的流行率降低，其他分枝杆菌的干扰在预防牛分枝杆菌根除方面发挥着越来越重要的作用。为了确定可能会干扰当前诊断测试的除牛分枝杆菌以外的分枝杆菌，进行了一项回顾性研究，以鉴定 2004 年 1 月 1 日至 2011 年 10 月 9 日期间在国家兽医服务实验室从临床组织中分离出的除牛分枝杆菌以外的分枝杆菌。
在研究期间，从提交用于牛分枝杆菌临床诊断的样本中分离出 2366 株除牛分枝杆菌以外的分枝杆菌。在此期间分离出 55 种分枝杆菌。在牛中，除牛分枝杆菌以外，从组织中分离出的主要分枝杆菌是鸟分枝杆菌复合体、偶发分枝杆菌/脓肿分枝杆菌复合体、耻垢分枝杆菌、堪萨斯分枝杆菌和胞内分枝杆菌复合体。从鹿中分离出的除牛分枝杆菌以外的分枝杆菌主要是鸟分枝杆菌复合体、胞内分枝杆菌/胞内分枝杆菌复合体和偶发分枝杆菌/脓肿分枝杆菌复合体。
这些数据提供了有关可能会干扰当前诊断测试的除牛分枝杆菌以外的分枝杆菌的物种和相对流行率的信息。
