Vanel D, Lacombe M J, Couanet D, Kalifa C, Spielmann M, Genin J
Radiology. 1987 Jul;164(1):243-5. doi: 10.1148/radiology.164.1.3588913.
Magnetic resonance (MR) imaging was used as a follow-up technique in 60 patients who underwent surgery and/or radiation therapy for primary malignant musculoskeletal tumors. MR imaging was performed on a 1.5-T imager with T1- and T2-weighted imaging sequences; MR imaging findings were confirmed by means of posttreatment surgery and histologic analysis or follow-up for at least 1 year. If a low-signal-intensity lesion was seen on T2-weighted images in a patient who had undergone radiation therapy or surgery, the patient usually did not have active tumor (sensitivity, 96%). If a high-signal-intensity lesion was seen after a patient had undergone only surgery, the patient had active tumor (six of six such cases). In patients who had undergone only radiation therapy, however, the presence of a high-signal-intensity lesion may indicate either active tumor or radiation-induced inflammatory changes. Thus, in such cases, differential diagnosis of active tumor may be difficult, if not impossible, to make from MR images.
磁共振（MR）成像被用作60例接受原发性恶性肌肉骨骼肿瘤手术和/或放射治疗患者的随访技术。MR成像在一台1.5-T成像仪上采用T1加权和T2加权成像序列进行；MR成像结果通过治疗后手术和组织学分析或至少1年的随访得到证实。如果在接受放射治疗或手术的患者的T2加权图像上看到低信号强度病变，该患者通常没有活动性肿瘤（敏感性为96%）。如果在仅接受手术的患者术后看到高信号强度病变，则该患者有活动性肿瘤（6例此类病例均如此）。然而，在仅接受放射治疗的患者中，高信号强度病变的出现可能表明是活动性肿瘤或放射诱导的炎症改变。因此，在这种情况下，从MR图像上鉴别活动性肿瘤即使不是不可能，也可能很困难。
