Bonneau M
Reprod Nutr Dev (1980). 1987;27(2A):413-22. doi: 10.1051/rnd:19870304.
The aim of the present experiment was to determine whether age, live weight, or a combination of both, was the most important factor influencing fat 5 alpha-androstenone levels in male pigs. Three groups of 50 boars each were fed either on a liberal plane of nutrition (CTRL group) or were restricted (SW and SA groups). Fat 5 alpha-androstenone was measured three times in each pig (on biopsies at two different times and at slaughter) at either the same live weight (SW) or at the same age (SA) as CTRL boars. In addition, the genital tract was dissected at slaughter. SW boars (aged 169 days) exhibited higher fat 5 alpha-androstenone levels than CTRL boars (aged 139 days) when the first biopsy was taken at 80 kg of live weight (1.2 vs 0.8 microgram/g; P less than 0.05). By the time of the second biopsy (100 kg of live weight) and at slaughter (125 kg) there was no significant difference between the SW and CTRL groups, although the SW were 43-55 days older than the CTRL. At all three measurement times, fat 5 alpha-androstenone was lower in SA than in CTRL boars which were 21-36 kg heavier (0.5 vs 0.8 micrograms/g at 139 days; 0.9 vs 1.3 micrograms/g at 160 days; 1.2 vs 2.0 micrograms/g at 185 days; P less than 0.001). Partial correlations between fat 5 alpha-androstenone and age were significant at the first biopsy, whereas partial correlations with live weight were significant at all three times of measurement. In SA boars weighing 90 kg there was a significant correlation between fat 5 alpha-androstenone and all the developmental traits of the genital tract. In SW and CTRL pigs weighing 125 kg, fat 5 alpha-androstenone was significantly correlated with accessory sex gland development but not with testis or epididymis weight. From the present data it is concluded that both age and live weight had a significant effect on fat 5 alpha-androstenone levels in young, light boars. In older, heavier boars, age had no effect per se but live weight still had a significant influence on 5 alpha-androstenone concentrations. In boars weighing 90 kg, fat 5 alpha-androstenone level depended on sexual maturity. When the animals were sexually mature at 125 kg of live weight, 5 alpha-androstenone level depended on the individual's potentiality for steroid production, which is probably under genetic control.
本实验的目的是确定年龄、活重或两者的组合是否是影响雄性猪脂肪中5α-雄烯酮水平的最重要因素。将三组每组50头公猪分别以自由采食营养水平（对照组）或限饲（SW组和SA组）。在每头猪的相同活重（SW）或相同年龄（SA）（与对照公猪相比）下，对每头猪的脂肪5α-雄烯酮进行三次测量（在两个不同时间的活检时以及屠宰时）。此外，在屠宰时解剖生殖道。当首次活检时活重达到80 kg时，SW组公猪（169日龄）的脂肪5α-雄烯酮水平高于对照组公猪（139日龄）（1.2对0.8微克/克；P<0.05）。到第二次活检时（活重100 kg）和屠宰时（125 kg），SW组和对照组之间没有显著差异，尽管SW组比对照组大43 - 55天。在所有三个测量时间点，SA组公猪的脂肪5α-雄烯酮水平均低于对照组公猪，后者体重重21 - 36 kg（139日龄时为0.5对0.8微克/克；160日龄时为0.9对1.3微克/克；185日龄时为1.2对2.0微克/克；P<0.001）。在首次活检时，脂肪5α-雄烯酮与年龄之间的偏相关性显著，而在所有三个测量时间点，与活重的偏相关性均显著。在体重90 kg的SA组公猪中，脂肪5α-雄烯酮与生殖道的所有发育特征之间存在显著相关性。在体重125 kg的SW组和对照组猪中，脂肪5α-雄烯酮与附属性腺发育显著相关，但与睾丸或附睾重量无关。根据目前的数据得出结论，年龄和活重对年轻、体重较轻的公猪脂肪中5α-雄烯酮水平均有显著影响。在年龄较大、体重较重的公猪中，年龄本身没有影响，但活重对5α-雄烯酮浓度仍有显著影响。在体重90 kg的公猪中，脂肪5α-雄烯酮水平取决于性成熟度。当动物在活重125 kg时达到性成熟，5α-雄烯酮水平取决于个体的类固醇生成潜力，这可能受遗传控制。
