Chandra Deb Liton, McGrath Brenda M, Schlosser Levi, Hewitt Austin, Schweitzer Connor, Rotar Jeff, Leedahl Nathan D, Crosby Ross, Carson Paul
Department of Public Health, North Dakota State University, Fargo, North Dakota, USA.
North Dakota Department of Health, Bismarck, North Dakota, USA.
Open Forum Infect Dis. 2022 Jun 17;9(7):ofac302. doi: 10.1093/ofid/ofac302. eCollection 2022 Jul.
Most antibiotics are prescribed in the ambulatory setting with estimates that up to 50% of use is inappropriate. Understanding factors associated with antibiotic misuse is essential to advancing better stewardship in this setting. We sought to assess the frequency of unnecessary antibiotic use for upper respiratory infections (URIs) among primary care providers and identify patient and provider characteristics associated with misuse.
Unnecessary antibiotic prescribing was assessed in a descriptive study by using adults ≥18 years seen for common URIs in a large, Upper Midwest, integrated health system, electronic medical records from June 2017 through May 2018. Individual provider rates of unnecessary prescribing were compared for primary care providers practicing in the departments of internal medicine, family medicine, or urgent care. Patient and provider characteristics associated with unnecessary prescribing were identified with a logistic regression model.
A total of 49 463 patient encounters were included. Overall, antibiotics were prescribed unnecessarily for 42.2% (95% confidence interval [CI], 41.7-42.6) of the encounters. Patients with acute bronchitis received unnecessary antibiotics most frequently (74.2%; 95% CI, 73.4-75.0). Males and older patients were more likely to have an unnecessary antibiotic prescription. Provider characteristics associated with higher rates of unnecessary prescribing included being in a rural practice, having more years in practice, and being in higher volume practices such as an urgent care setting. Fifteen percent of providers accounted for half of all unnecessary antibiotic prescriptions.
Although higher-volume practices, a rural setting, or longer time in practice were predictors, unnecessary prescribing was common among all providers.
大多数抗生素是在门诊环境中开具的,据估计,高达50%的抗生素使用是不恰当的。了解与抗生素滥用相关的因素对于在这种环境中推进更好的管理至关重要。我们试图评估初级保健提供者中对上呼吸道感染(URI)不必要使用抗生素的频率,并确定与滥用相关的患者和提供者特征。
在一项描述性研究中,通过使用2017年6月至2018年5月期间在中西部上游一个大型综合卫生系统中因常见URI就诊的≥18岁成年人的电子病历,评估不必要的抗生素处方。比较了在内科、家庭医学或紧急护理部门执业的初级保健提供者的个体不必要处方率。通过逻辑回归模型确定与不必要处方相关的患者和提供者特征。
共纳入49463次患者就诊。总体而言,42.2%(95%置信区间[CI],41.7 - 42.6)的就诊被不必要地开具了抗生素。急性支气管炎患者最常接受不必要的抗生素治疗(74.2%;95%CI,73.4 - 75.0)。男性和老年患者更有可能接受不必要的抗生素处方。与较高不必要处方率相关的提供者特征包括在农村执业、执业年限较长以及在诸如紧急护理环境等高工作量的执业环境中工作。15%的提供者开具了所有不必要抗生素处方的一半。
虽然高工作量的执业环境、农村环境或较长的执业时间是预测因素,但不必要的处方在所有提供者中都很常见。