Bisbee Charles A, Burstiner Logan, Natcheva Hristina
Radiology, Nova Southeastern University Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Radiology, University of South Florida, Tampa, USA.
Cureus. 2022 Jun 21;14(6):e26155. doi: 10.7759/cureus.26155. eCollection 2022 Jun.
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Classically, HEHE is typically associated with imaging demonstrating multifocal heterogeneously enhancing hepatic nodules and histologic examination revealing mixed epithelioid and dendritic cells in a proliferative fibrous stromal background. While generally described as a low-to-intermediate grade indolent tumor, it is essential to establish the presence or absence of extrahepatic spread when considering transplant candidacy. We describe one case study in which a transplant was denied to a unique metastatic pattern of HEHE to the superior vena cava. This is a previously unreported location of metastasis of HEHE and may serve to broaden our current understanding of potential metastatic sites for this disease.
肝上皮样血管内皮瘤（HEHE）是一种罕见的血管源性恶性肿瘤。传统上，HEHE通常与影像学表现为多灶性不均匀强化的肝结节以及组织学检查显示在增生性纤维基质背景中存在混合的上皮样细胞和树突状细胞相关。虽然通常被描述为低至中级别的惰性肿瘤，但在考虑移植候选资格时，确定是否存在肝外转移至关重要。我们描述了一个病例研究，其中一名患者因HEHE转移至上腔静脉的独特转移模式而被拒绝进行移植。这是HEHE先前未报道的转移部位，可能有助于拓宽我们目前对该疾病潜在转移部位的认识。
