Ferraioli Giovanna, Raimondi Ambra, Maiocchi Laura, De Silvestri Annalisa, Filice Carlo
Dipartimento di Scienze Clinico-Chirurgiche, Diagnostiche e Pediatriche, Università di Pavia, Viale Brambilla 74, 27100 Pavia, Italy.
Dipartimento di Scienze Mediche e Malattie Infettive, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100 Pavia, Italy.
Diagnostics (Basel). 2022 Jul 23;12(8):1787. doi: 10.3390/diagnostics12081787.
Background: The primary aim of our study was to assess the correlation between an improved version of the attenuation coefficient available on the Arietta 850 ultrasound system (iATT, Fujifilm Healthcare, Tokyo, Japan) and controlled attenuation parameter (CAP). The secondary aim was to assess whether focusing only on iATT acquisition without following the strict protocol for liver stiffness measurements would affect iATT measurement. Methods: Consecutive individuals were enrolled. Pearson’s r was used to test the correlation between ATT and CAP values. The concordance between iATT and CAP was tested using Lin’s concordance correlation coefficient (CCC). Results: 354 individuals (203 males, 151 females) were studied. The overall Pearson correlation between CAP and iATT values obtained following or not following the liver stiffness measurement protocol, respectively, were r = 0.73 and r = 0.71. The correlation was affected by the interquartile range/median (IQR/M) of the 10 measurements: it was r = 0.75 for IQR/M ≤ 15% and r = 0.60 for IQR/M > 15%. CCC showed that there was a moderate to good concordance between iATT and CAP values. Conclusion: iATT shows a strong correlation with CAP that does not decrease when the protocol for liver stiffness acquisition is not followed. The correlation between iATT and CAP values is higher when the IQR/M ≤ 15%.
我们研究的主要目的是评估Arietta 850超声系统（日本东京富士胶片医疗保健公司的iATT）上可用的改进版衰减系数与受控衰减参数（CAP）之间的相关性。次要目的是评估仅专注于iATT采集而不遵循肝脏硬度测量的严格方案是否会影响iATT测量。方法：纳入连续的个体。使用Pearson相关系数r来检验ATT与CAP值之间的相关性。使用Lin一致性相关系数（CCC）来检验iATT与CAP之间的一致性。结果：研究了354名个体（203名男性，151名女性）。分别遵循或不遵循肝脏硬度测量方案获得的CAP与iATT值之间的总体Pearson相关性分别为r = 0.73和r = 0.71。相关性受10次测量的四分位数间距/中位数（IQR/M）影响：IQR/M≤15%时r = 0.75，IQR/M>15%时r = 0.60。CCC表明iATT与CAP值之间存在中度至良好的一致性。结论：iATT与CAP显示出很强的相关性，在不遵循肝脏硬度采集方案时不会降低。当IQR/M≤15%时，iATT与CAP值之间的相关性更高。
