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脊髓血管分流术:单中心系列研究及文献综述之分类

Spinal Vascular Shunts: Single-Center Series and Review of the Literature of Their Classification.

作者信息

Lizana Jafeth, Aliaga Nelida, Marani Walter, Escribano Amanda, Montemurro Nicola

机构信息

Department of Neurosurgery, Hospital Nacional Guillermo Almenara Irigoyen, Lima 07035, Peru.

Department of Medicine, School of Biomedical Sciences, Austral University, Buenos Aires B1751, Argentina.

出版信息

Neurol Int. 2022 Jul 15;14(3):581-599. doi: 10.3390/neurolint14030047.

Abstract

Spinal arteriovenous shunts (sAVSs) are an uncommon disease, constituting 3 to 4% of intradural lesions; 70% of these lesions are spinal arteriovenous fistulas (sAVFs), whereas spinal arteriovenous malformations (sAVMs) are rarer. Both share the problem of their classification due to the heterogeneity of their angioarchitecture. The aim of this study is to report a series of sAVSs treated in the neurosurgery department of the Hospital Nacional Guillermo Almenara during the 2018-2020 period and to present an overview of the current literature on sAVS classification. We reviewed all medical records of patients diagnosed with sAVFs and sAVMs during the 2018-2020 period, and then we analyzed images with Horos v4.0.0, illustrated some cases with Clip Studio Paint v1.10.5, and performed a descriptive statistical analysis with SPSS v25. Twelve patients were included in this study, eight of which were women (67%) and four of which were men (33%); the age range was from 3 to 74 years. Eight sAVSs were sAVFs, whereas four were sAVMs. The most frequent clinical manifestation was chronic myelopathy in seven patients (58%). Of those treated only by embolization, seven (70%) resulted in complete occlusion (five sAVFs and two sAVMs), while three (30%) remained with a residual lesion. At last follow-up, five patients (42%) improved clinically, and the seven remaining (58%) maintained the same neurological state. sAVSs require a detailed study of their angioarchitecture for proper management. The endovascular treatment is safe with acceptable cure rates. The surgical option should not be set aside.

摘要

脊髓动静脉分流(sAVS)是一种罕见疾病,占硬膜内病变的3%至4%;其中70%的病变为脊髓动静脉瘘(sAVF),而脊髓动静脉畸形(sAVM)则更为罕见。由于其血管结构的异质性,两者都存在分类问题。本研究的目的是报告2018 - 2020年期间在国立吉列尔莫·阿尔梅纳拉医院神经外科治疗的一系列sAVS病例,并概述当前关于sAVS分类的文献。我们回顾了2018 - 2020年期间诊断为sAVF和sAVM的患者的所有病历,然后使用Horos v4.0.0分析图像,用Clip Studio Paint v1.10.5展示一些病例,并使用SPSS v25进行描述性统计分析。本研究纳入了12例患者,其中8例为女性(67%),4例为男性(33%);年龄范围为3至74岁。8例sAVS为sAVF,4例为sAVM。最常见的临床表现是7例患者(58%)出现慢性脊髓病。在仅接受栓塞治疗的患者中,7例(70%)实现了完全闭塞(5例sAVF和2例sAVM),而3例(30%)仍有残留病变。在最后一次随访时,5例患者(42%)临床症状改善,其余7例(58%)神经状态保持不变。sAVS需要对其血管结构进行详细研究以进行恰当管理。血管内治疗安全且治愈率可接受。手术选择也不应被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7050/9326594/f3b63b16afcd/neurolint-14-00047-g001.jpg

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