Chou Hui-Chuan, Tsai Hui-Yu, Sun Tzu-Chin, Lin Mei-Feng
BSN, RN, Case Manager, Department of Cancer Center, China Medical University Hsinchu Hospital, Taiwan, ROC.
BSN, RN, Graduate Student, College of Medicine, Department of Nursing, National Cheng Kung University, Taiwan, ROC.
Hu Li Za Zhi. 2022 Aug;69(4):75-87. doi: 10.6224/JN.202208_69(4).10.
Acupressure is one of the recommended non-pharmacologic treatments for cancer-related fatigue (CRF) according to the National Comprehensive Cancer Network guidelines. However, few systematic review or meta-analysis studies have focused on the effect of acupressure on CRF.
The purpose of this study was to examine the effectiveness of acupressure in reducing CRF and to identify the effective acupoints and frequencies of acupressure treatments.
The search and screening procedures were conducted in accordance with PRISMA 2009 guidelines. The search database included Embase, CINAHL, Cochrane Library, MEDLINE and Google Scholar. RoB 2.0 and ROBINS-I were used as appraisal tools. The statistical analysis, including effect size estimation, was computed using RevMan 5.4.
Twelve studies (15 sets of data) were included in the review and analysis. Nine hundred sixty patients with cancer who were currently undergoing or had completed treatment were enrolled as participants and received different levels of acupressure. The result showed the overall effect size of CRF in reducing acupressure to be SMD= -0.77, 95% CI [-0.90, -0.65]. In the subgroup analysis, the effect size of auricular acupressure was SMD= -0.98, 95% CI [-1.25, -0.71] and the body acupressure effect size was SMD= -0.70, 95% CI [-0.84, -0.56].
CONCLUSIONS / IMPLICATIONS FOR PRACTICE: Based on the results of this systematic review, acupressure may be applied to the body acupoints Hegu (LI4), Zusanli (ST36), and Sanyinjiao (SP6) once daily for 1-3 minutes each and to the auricular acupoints shenmen and subcortex once daily for 3 minutes each to effectively reduce cancer-related fatigue.
根据美国国立综合癌症网络指南，指压是推荐用于癌症相关疲劳（CRF）的非药物治疗方法之一。然而，很少有系统评价或荟萃分析研究关注指压对CRF的影响。
本研究旨在探讨指压在减轻CRF方面的有效性，并确定有效的穴位和指压治疗频率。
检索和筛选程序按照PRISMA 2009指南进行。检索数据库包括Embase、CINAHL、Cochrane图书馆、MEDLINE和谷歌学术。使用RoB 2.0和ROBINS-I作为评估工具。使用RevMan 5.4进行包括效应量估计在内的统计分析。
12项研究（15组数据）纳入综述和分析。960名正在接受或已完成治疗的癌症患者作为参与者，接受了不同程度的指压。结果显示，指压减轻CRF的总体效应量为SMD = -0.77，95%CI[-0.90，-0.65]。在亚组分析中，耳穴指压的效应量为SMD = -0.98，95%CI[-1.25，-0.71]，体穴指压的效应量为SMD = -0.70，95%CI[-0.84，-0.56]。
结论/实践意义：基于本系统评价的结果，指压可应用于合谷（LI4）、足三里（ST36）和三阴交（SP6）等体穴，每天一次，每次1 - 3分钟，以及神门和皮质下等耳穴，每天一次，每次3分钟，以有效减轻癌症相关疲劳。
