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非结核分枝杆菌:生态学及其对动物和人类健康的影响

Nontuberculous Mycobacteria: Ecology and Impact on Animal and Human Health.

作者信息

Pavlik Ivo, Ulmann Vit, Falkinham Joseph O

机构信息

Faculty of Regional Development and International Studies, Mendel University in Brno, Tr. Generala Piky 7, 613 00 Brno, Czech Republic.

Public Health Institute Ostrava, Partyzanske Nam. 7, 702 00 Ostrava, Czech Republic.

出版信息

Microorganisms. 2022 Jul 27;10(8):1516. doi: 10.3390/microorganisms10081516.

Abstract

Nontuberculous mycobacteria (NTM) represent an important group of environmentally saprophytic and potentially pathogenic bacteria that can cause serious mycobacterioses in humans and animals. The sources of infections often remain undetected except for soil- or water-borne, water-washed, water-based, or water-related infections caused by groups of the complex; and other NTM species, including infection, known as fish tank granuloma, and infection, which is described as a Buruli ulcer. NTM could be considered as water-borne, air-borne, and soil-borne pathogens (sapronoses). A lot of clinically relevant NTM species could be considered due to the enormity of published data on permanent, periodic, transient, and incidental sapronoses. Interest is currently increasing in mycobacterioses diagnosed in humans and husbandry animals (esp. pigs) caused by NTM species present in peat bogs, potting soil, garden peat, bat and bird guano, and other matrices used as garden fertilizers. NTM are present in dust particles and in water aerosols, which represent certain factors during aerogenous infection in immunosuppressed host organisms during hospitalization, speleotherapy, and leisure activities. For this Special Issue, a collection of articles providing a current view of the research on NTM-including the clinical relevance, therapy, prevention of mycobacterioses, epidemiology, and ecology-are addressed.

摘要

非结核分枝杆菌(NTM)是一类重要的环境腐生菌和潜在病原菌,可导致人类和动物发生严重的分枝杆菌病。除了由该菌群引起的土壤传播、水洗、水基或与水相关的感染,以及其他NTM菌种引起的感染(如鱼缸肉芽肿和被描述为布鲁里溃疡的感染)外,感染源往往难以察觉。NTM可被视为水传播、空气传播和土壤传播的病原体(腐生病原)。鉴于关于持续性、周期性、短暂性和偶发性腐生病原的已发表数据数量庞大,许多具有临床相关性的NTM菌种都值得关注。目前,人们对泥炭沼泽、盆栽土壤、园艺泥炭、蝙蝠和鸟类粪便以及用作园艺肥料的其他基质中存在的NTM菌种引起的人类和饲养动物(尤其是猪)分枝杆菌病的诊断兴趣日益浓厚。NTM存在于尘埃颗粒和水气溶胶中,在住院、洞穴疗法和休闲活动期间,这些在免疫抑制宿主生物体的空气传播感染中代表了某些因素。本期特刊收录了一系列文章,对NTM的研究现状进行了阐述,内容包括临床相关性、治疗、分枝杆菌病的预防、流行病学和生态学。

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Microorganisms. 2022 Jul 3;10(7):1345. doi: 10.3390/microorganisms10071345.
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Ecology of Nontuberculous Mycobacteria.非结核分枝杆菌生态学
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