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比较因 SARS-COV2 住院的老年和超高龄老年患者的临床特征。

A comparison of clinical characteristics between old and oldest-old patients hospitalised for SARS-COV2.

机构信息

Department of Geriatric Medicine, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Department of Geriatric Medicine, CHU UCL Namur Hospital, Godinne site, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Acta Clin Belg. 2023 Jun;78(3):192-199. doi: 10.1080/17843286.2022.2102115. Epub 2022 Jul 27.

Abstract

OBJECTIVES

Oldest-old patients may have an unusual SARS-COV2 presentation that can jeopardise diagnosis and management. The aim of this study was to compare the clinical characteristics and outcomes of oldest-old (≥85 years) and old patients (75-85 years) admitted with COVID-19 to Belgian hospitals during the first wave of the pandemic.

METHODS

We conducted a multicentre, retrospective, observational study in ten Belgian hospitals. We reviewed the electronic clinical records of patients ≥75 years hospitalised with COVID-19 from March to June 2020.

RESULTS

A total of 986 patients were placed on the register (old group: n = 507; oldest-old group: n = 479). Before hospitalisation, the oldest-old (OO) group presented with more geriatric syndromes including comorbidities, frailty, falls, cognitive impairment, and incontinence. At admission, the OO group presented with less cough, less headache, and less fever but significantly more delirium than old (O) group. Members of the OO group were admitted less frequently to intensive care units (ICUs). A geriatrician was consulted to help in the decision-making process more often for the OO group. The global mortality of the cohort was 47%, with no difference between the two groups. Patients in the OO group were more often institutionalised after hospitalisation and less often referred for rehabilitation.

CONCLUSIONS

The OO patients presented with more geriatric syndromes that make them vulnerable to dependence and institutionalisation after a hospital stay, without having a higher mortality rate than O patients. Geriatrician expertise is necessary in the management of frail older patients.

摘要

目的

最年长的老年患者可能具有不寻常的严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)表现,这可能危及诊断和治疗。本研究的目的是比较比利时医院在大流行第一波期间收治的最年长(≥85 岁)和年长(75-85 岁)的 COVID-19 患者的临床特征和结局。

方法

我们在比利时的 10 家医院进行了一项多中心、回顾性、观察性研究。我们回顾了 2020 年 3 月至 6 月期间因 COVID-19 住院的≥75 岁患者的电子临床记录。

结果

共登记了 986 名患者(老年组:n = 507;最年长老年组:n = 479)。在住院前,最年长老年组(OO 组)出现了更多的老年综合征,包括合并症、衰弱、跌倒、认知障碍和失禁。在入院时,OO 组的咳嗽、头痛和发热症状较少,但谵妄发生率显著高于老年组(O 组)。OO 组患者入住重症监护病房(ICU)的频率较低。OO 组更常请老年病专家协助决策。该队列的总体死亡率为 47%,两组之间无差异。住院后,OO 组的患者更多地被安置在医疗机构中,而较少被转介到康复机构。

结论

OO 组患者出现了更多的老年综合征,使他们在住院后更容易依赖和被安置在医疗机构中,但死亡率并不高于 O 组。老年病专家的专业知识对于脆弱的老年患者的管理是必要的。

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