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新技术大规模研究神经肽。

New Technologies to Investigate Neuropeptides at Scale.

机构信息

Institute of Pharmacology and Toxicology and Neuroscience Center Zurich, University of Zürich, Zürich CH-8057, Switzerland.

Neuroscience Center Zurich, University and ETH Zürich, Zürich CH-8057, Switzerland.

出版信息

ACS Chem Neurosci. 2022 Aug 17;13(16):2353-2355. doi: 10.1021/acschemneuro.2c00394. Epub 2022 Jul 27.

Abstract

Neuropeptides are some of the most elusive molecules to monitor in neuroscience. Detecting their release and spread in brain tissue requires the development and use of advanced technologies that enable specific neuropeptide measurements with high spatial and temporal resolution. This Viewpoint highlights some of the emerging tools and techniques that are already advancing our knowledge of neuropeptide physiology and discusses possible future developments.

摘要

神经肽是神经科学中最难监测的分子之一。要检测其在脑组织中的释放和扩散,需要开发和使用先进的技术,这些技术能够以高时空分辨率进行特定的神经肽测量。本观点强调了一些新兴的工具和技术,这些工具和技术正在推动我们对神经肽生理学的认识,并讨论了可能的未来发展。

相似文献

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New Technologies to Investigate Neuropeptides at Scale.新技术大规模研究神经肽。
ACS Chem Neurosci. 2022 Aug 17;13(16):2353-2355. doi: 10.1021/acschemneuro.2c00394. Epub 2022 Jul 27.
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Current and emerging methods for probing neuropeptide transmission.当前和新兴的神经肽传递探测方法。
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Emerging approaches for decoding neuropeptide transmission.新兴的神经肽传递解码方法。
Trends Neurosci. 2022 Dec;45(12):899-912. doi: 10.1016/j.tins.2022.09.005. Epub 2022 Oct 15.

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