Cascaes Andreia Morales, Silva Nathalia Ribeiro Jorge da, Fernandez Matheus Dos Santos, Bomfim Rafael Aiello, Vaz Juliana Dos Santos
Federal University of Santa Catarina, Department of Public Health, Graduate Program in Public Health, Graduate Program in Dentistry, Florianópolis, SC, Brazil.
Federal University of Pelotas, Faculty of Dentistry, Graduate Program in Dentistry, Pelotas, RS, Brazil.
Br J Nutr. 2022 Jul 27:1-10. doi: 10.1017/S0007114522002409.
This study summarised the association between ultra-processed food (UPF) consumption and dental caries in children and adolescents through a systematic review and meta-analysis. The search of PubMed, Cochrane, Web of Science and Scopus databases using the 'PECOS' strategy retrieved 1462 eligible articles. Only studies with humans aged ≤ 19 years; that assessed groups of any UPF or specific UPF items; that measured dental caries as the decayed, filled and missing surfaces or teeth indexes, based on the WHO criteria; cross-sectional, case-control, cohort and all types of interventions that examined the adjusted association between UPF consumption and dental caries were included. All studies received qualitative evaluation. Meta-analysis using random-effects models combined multivariable-adjusted OR for case-control and cross-sectional studies and risk ratio (RR) for longitudinal studies of the highest . lowest category of UPF consumption. Forty-two studies were included in the qualitative synthesis and twenty-seven in the meta-analysis. The pooled RR was 1·71 (95 % CI 1·31, 2·24), and the pooled OR was 1·55 (95 % CI 1·37, 1·75). The highest OR was found among participants who had dental caries prevalence >70 % (OR = 3·67, 95 % CI 2·16, 6·23). Better evidence quality was found among cohort studies that evaluated children <6 years old. The findings suggest that higher UPF consumption is associated with greater dental caries in children and adolescents. Public health efforts to reduce UPF consumption are needed to improve the oral health of children and adolescents.
本研究通过系统评价和荟萃分析总结了儿童和青少年超加工食品（UPF）消费与龋齿之间的关联。使用“PECOS”策略检索PubMed、Cochrane、Web of Science和Scopus数据库，共检索到1462篇符合条件的文章。纳入的研究对象为年龄≤19岁的人群；评估任何UPF或特定UPF项目组；根据世界卫生组织标准，将龋齿测量为龋、补、失牙面或牙齿指数；横断面研究、病例对照研究、队列研究以及所有类型的干预研究，这些研究均考察了UPF消费与龋齿之间的校正关联。所有研究均接受了定性评估。使用随机效应模型进行荟萃分析，合并了病例对照研究和横断面研究的多变量校正比值比（OR）以及纵向研究中UPF消费最高、最低类别之间的风险比（RR）。定性综合分析纳入了42项研究，荟萃分析纳入了27项研究。汇总RR为1.71（95%CI 1.31, 2.24），汇总OR为1.55（95%CI 1.37, 1.75）。在龋齿患病率>70%的参与者中发现了最高的OR（OR = 3.67, 95%CI 2.16, 6.23）。在评估6岁以下儿童的队列研究中发现了更好的证据质量。研究结果表明，儿童和青少年中较高的UPF消费量与更高的龋齿发生率相关。需要通过公共卫生措施减少UPF消费，以改善儿童和青少年的口腔健康。
