MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, China.
Guangzhou Key Laboratory of Spectral Analysis and Functional Probes, College of Biophotonics, South China Normal University, Guangzhou, China.
Luminescence. 2022 Oct;37(10):1733-1740. doi: 10.1002/bio.4349. Epub 2022 Aug 11.
Here we investigate the aggregation behaviours of three prepared dyes in the liquid phase to pick out one possessing J-aggregation characteristic that is of significant interest for organic materials used in multiple bio-applications. The self-assembly of dyes usually leads to various forms of aggregates, for example, H-aggregates or J-aggregates and it is easy to distinguish bathochromic J-aggregation from hypsochromic H-aggregation using UV/vis light spectroscopy. Enlightened by the cyanine dyes that have shown a great tendency to self-associate, we designed and synthesized three cyanine dyes: Cy7-Ph, DCy7-Ph, and SN-Cy7-Ph, followed by the study of the influence of multiple factors on their aggregation behaviours, including solvent polarity, ionic strength, and temperature. Finally, we found that of the three molecules only SN-Cy7-Ph could self-assemble into J-aggregates conveniently and stably in the aqueous phase under normal conditions.
在这里，我们研究了三种制备染料在液相中的聚集行为，以挑选出一种具有 J-聚集特性的染料，这种特性对于用于多种生物应用的有机材料具有重要意义。染料的自组装通常会导致各种形式的聚集体，例如 H-聚集体或 J-聚集体，并且可以使用紫外/可见光谱很容易地区分红移的 J-聚集体和蓝移的 H-聚集体。受表现出强烈自组装倾向的花菁染料的启发，我们设计并合成了三种花菁染料：Cy7-Ph、DCy7-Ph 和 SN-Cy7-Ph，随后研究了多种因素对它们聚集行为的影响，包括溶剂极性、离子强度和温度。最后，我们发现这三种分子中只有 SN-Cy7-Ph 能够在正常条件下在水相中方便、稳定地自组装成 J-聚集体。
