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老年患者贫血。

Anemia of geriatric patients.

机构信息

1 Department of Clinical Studies, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary.

2 Department of Geriatrics and Center of Nursing Sciences, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary.

出版信息

Physiol Int. 2022 Jun 7;109(2):119-134. doi: 10.1556/2060.2022.00218. Print 2022 Jun 16.

Abstract

Anemia is a common finding in the elderly. Approximately 10 percent of the elderly suffers from anemia. Anemia per se is an independent factor of mortality in older patients regardless its cause. Frailty is also frequent in geriatric patients. That means that there is a decreased reserve capacity to react to different stress factors including anemia. The frequent presence of heart failure and also impaired cerebrovascular circulation makes more difficult to tolerate anemia in older age. Anemia is a symptom, finding and treating the underlying cause is also important. Treatment always depends on clinical findings: the more severe the symptoms, the more important to treat them. Severity of anemia depends not only the underlying cause, degree of anemia, co-morbidities and frailty of the patients, but also the speed of its development. Sudden blood loss due to an accident is less well tolerated than the same degree of anemia due to B12 deficiency. Main causes of anemia in the elderly include nutritional deficiencies, chronic diseases, tumors, and certain hematological malignancies such as chronic lymphocytic leukemia, multiple myeloma, myelodysplastic syndrome.

摘要

贫血在老年人中很常见。大约 10%的老年人患有贫血。贫血本身是老年患者死亡的一个独立因素,无论其原因如何。虚弱在老年患者中也很常见。这意味着他们对包括贫血在内的不同应激因素的反应储备能力下降。心力衰竭和脑血管循环受损的频繁发生使得老年人更难以耐受贫血。贫血是一种症状,寻找和治疗潜在原因也很重要。治疗总是取决于临床发现:症状越严重,治疗就越重要。贫血的严重程度不仅取决于潜在的病因、贫血的程度、患者的合并症和虚弱程度,还取决于其发展速度。由于意外事故导致的急性失血比由于缺乏维生素 B12 导致的相同程度的贫血更难耐受。老年人贫血的主要原因包括营养缺乏、慢性疾病、肿瘤以及某些血液系统恶性肿瘤,如慢性淋巴细胞白血病、多发性骨髓瘤、骨髓增生异常综合征。

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