Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NC.
Department of Veterinary Administration, College of Veterinary Medicine, Purdue University, West Lafayette, IN.
Am J Vet Res. 2022 Jul 23;83(9):ajvr.22.03.0039. doi: 10.2460/ajvr.22.03.0039.
To evaluate the influence of superficial digital flexor tendon (SDFT) graft augmentation on the biomechanical properties and resistance to gap formation in a canine gastrocnemius tendon repair model.
28 canine cadaveric hind limbs.
Respective hindlimbs from each dog were randomized to one of two groups (n = 14/group) using a 3-loop-pulley (3LP) pattern alone or 3LP + SDFT graft augmentation. Biomechanical parameters evaluated included yield, peak, and failure loads; tensile loads required to create 1- and 3-mm gap formations; and mode of construct failure.
Mean yield and failure loads for the 3LP + SDFT graft group were 483.6 ± 148.0 N and 478.3 ± 147.9 N, respectively, and were greater compared to the 3LP group (34.2 ± 6.7 N and 34.0 ± 8.0 N, P < .0001). Loads to both 1- and 3-mm gap formations for the 3LP + SDFT graft group were greater compared to 3LP alone (P < .001). Failure modes did not differ between groups (P = .120), with constructs failing most commonly by suture pulling through opposed tendinous tissues whereas SDFT grafts remained intact.
SDFT graft augmentation increased yield, peak, and failure forces 14-fold across all examined biomechanical variables compared to the 3LP group. The 3LP + SDFT graft group required 3.6X and 6.5X greater loads to cause a 1- and 3-mm gap, respectively, between tendon ends. These data support the biomechanical advantages of SDFT graft augmentation to increase repair-site strength and to promote resistance to gap formation of the tenorrhaphy. Additional in vivo studies are required to determine the effect of SDFT augmentation on clinical function and active limb use after graft harvest in dogs.
评估浅屈肌腱（SDFT）移植物增强对犬跟腱修复模型生物力学特性和抗间隙形成能力的影响。
28 只犬的后肢。
使用 3 圈滑轮（3LP）模式单独或 3LP+SDFT 移植物增强对每只狗的相应后肢进行分组（每组 14 只）。评估的生物力学参数包括屈服、峰值和失效载荷；产生 1 和 3mm 间隙所需的拉伸载荷；以及构建失败的模式。
3LP+SDFT 移植物组的平均屈服和失效载荷分别为 483.6±148.0N 和 478.3±147.9N，明显大于 3LP 组（34.2±6.7N 和 34.0±8.0N，P<0.0001）。3LP+SDFT 移植物组的 1 和 3mm 间隙形成的载荷均明显大于单独 3LP 组（P<0.001）。两组之间的失败模式没有差异（P=0.120），最常见的是缝线穿过对侧腱组织拉出，而 SDFT 移植物保持完整。
与 3LP 组相比，SDFT 移植物增强使所有检查的生物力学变量的屈服、峰值和失效力增加了 14 倍。3LP+SDFT 移植物组分别需要 3.6 倍和 6.5 倍的更大载荷才能在肌腱末端之间产生 1mm 和 3mm 的间隙。这些数据支持 SDFT 移植物增强在增加修复部位强度和促进肌腱吻合抗间隙形成方面的生物力学优势。需要进一步的体内研究来确定 SDFT 增强对狗在移植物采集后临床功能和主动肢体使用的影响。
