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胫骨后神经刺激治疗儿童下尿路功能障碍:体验、生活质量和治疗效果的混合方法分析。

Posterior Tibial Nerve Stimulation in Children with Lower Urinary Tract Dysfunction: A Mixed-Methods Analysis of Experiences, Quality of Life and Treatment Effect.

机构信息

Division of Pediatric Urology, Radboud University Medical Center, Amalia Children's Hospital, 6525 GA Nijmegen, The Netherlands.

Department of Urology, University Hospital Maastricht, 6229 HX Maastricht, The Netherlands.

出版信息

Int J Environ Res Public Health. 2022 Jul 25;19(15):9062. doi: 10.3390/ijerph19159062.

DOI:10.3390/ijerph19159062
PMID:35897438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9331059/
Abstract

BACKGROUND

Posterior tibial nerve stimulation (PTNS) is one of the treatment modalities for children with therapy-refractory lower urinary tract dysfunction (LUTD). This study used a mixed-methods analysis to gain insight into the experiences of children treated with PTNS and their parents, the effect of treatment on quality of life (QOL) and the effect of PTNS on urinary symptoms.

METHODS

Quantitative outcomes were assessed through a single-centre retrospective chart analysis of all children treated with PTNS in a group setting between 2016-2021. Voiding parameters and QOL scores before and after treatment were compared. Qualitative outcomes were assessed by an explorative study involving semi-structured interviews transcribed verbatim and inductively analysed using the constant-comparative method.

RESULTS

The data of 101 children treated with PTNS were analysed. Overall improvement of LUTD was seen in 42% and complete resolution in 10%. Average and maximum voided volumes significantly increased. QOL improved in both parents and children independent of the actual effect on urinary symptoms. Interviews revealed PTNS to be well-tolerated. Facilitating PTNS in a group setting led to feelings of recognition in both children and parents.

CONCLUSIONS

PTNS is a good treatment in children with therapy-refractory LUTD and provides valuable opportunities for peer support if given in a group setting.

摘要

背景

胫骨后神经刺激(PTNS)是治疗治疗抵抗性下尿路功能障碍(LUTD)儿童的治疗方法之一。本研究采用混合方法分析,深入了解接受 PTNS 治疗的儿童及其父母的治疗体验、治疗对生活质量(QOL)的影响以及 PTNS 对排尿症状的影响。

方法

通过对 2016-2021 年在一个小组环境中接受 PTNS 治疗的所有儿童的单中心回顾性图表分析评估定量结果。比较治疗前后的排尿参数和 QOL 评分。通过一项探索性研究评估定性结果,该研究涉及逐字转录的半结构化访谈,并使用恒定比较法进行归纳分析。

结果

分析了 101 名接受 PTNS 治疗的儿童的数据。42%的儿童 LUTD 总体改善,10%的儿童完全缓解。平均和最大排尿量显著增加。无论对排尿症状的实际影响如何,父母和儿童的 QOL 都有所改善。访谈显示 PTNS 耐受性良好。在小组环境中进行 PTNS 治疗为儿童和家长提供了同伴支持的宝贵机会。

结论

PTNS 是治疗治疗抵抗性 LUTD 儿童的一种很好的治疗方法,如果在小组环境中进行,可为提供同伴支持提供有价值的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d022/9331059/73f3904d503f/ijerph-19-09062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d022/9331059/73f3904d503f/ijerph-19-09062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d022/9331059/73f3904d503f/ijerph-19-09062-g001.jpg

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