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本文引用的文献

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Potential Shortages of Hydroxychloroquine for Patients with Lupus During the Coronavirus Disease 2019 Pandemic.2019年冠状病毒病大流行期间狼疮患者羟氯喹的潜在短缺情况。
JAMA Health Forum. 2020 Apr 1;1(4):e200438. doi: 10.1001/jamahealthforum.2020.0438.
2
Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States.美国 COVID-19 大流行期间常用药物的处方配药模式。
JAMA. 2020 Jun 23;323(24):2524-2526. doi: 10.1001/jama.2020.9184.
3
Therapeutic alternatives and strategies for drug conservation in the intensive care unit during times of drug shortage: a report of the Ontario COVID-19 ICU Drug Task Force.在药物短缺时期加强医疗单位药物管理的治疗选择和策略:安大略省 COVID-19 加强医疗单位药物特别工作组的报告。
Can J Anaesth. 2020 Oct;67(10):1405-1416. doi: 10.1007/s12630-020-01713-5. Epub 2020 May 26.
4
Global drug shortages due to COVID-19: Impact on patient care and mitigation strategies.全球因 COVID-19 导致的药品短缺:对患者护理的影响和缓解策略。
Res Social Adm Pharm. 2021 Jan;17(1):1946-1949. doi: 10.1016/j.sapharm.2020.05.017. Epub 2020 May 19.
5
Medication Shortages During the COVID-19 Crisis: What We Must Do.新冠疫情危机期间的药品短缺:我们必须采取的措施。
Mayo Clin Proc. 2020 Jun;95(6):1112-1115. doi: 10.1016/j.mayocp.2020.04.001. Epub 2020 Apr 3.
6
Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.意大利伦巴第地区 1591 名 ICU 收治的 SARS-CoV-2 感染患者的基线特征和结局。
JAMA. 2020 Apr 28;323(16):1574-1581. doi: 10.1001/jama.2020.5394.
7
Longitudinal trends in U.S. shortages of sterile solutions, 2001-17.2001 - 2017年美国无菌溶液短缺情况的纵向趋势
Am J Health Syst Pharm. 2018 Dec 1;75(23):1903-1908. doi: 10.2146/ajhp180203.
8
ASHP Guidelines on Managing Drug Product Shortages in Hospitals and Health Systems.美国卫生系统药师协会关于医院及卫生系统药品短缺管理的指南
Am J Health Syst Pharm. 2009 Aug 1;66(15):1399-406. doi: 10.2146/ajhp090026.

在新冠疫情期间创建国家药品短缺信息平台。

Creation of a State Drug Shortage Dashboard in the COVID-19 Pandemic.

作者信息

Lux Kristin, Jorns Melinda, Vogler Carrie

机构信息

Southern Illinois University Edwardsville School of Pharmacy, Edwardsville, IL, USA.

出版信息

Hosp Pharm. 2022 Aug;57(4):474-481. doi: 10.1177/00185787211046861. Epub 2021 Sep 24.

DOI:10.1177/00185787211046861
PMID:35898256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9310306/
Abstract

Drug shortages are anticipated to worsen with time as the Coronavirus Disease 2019 (COVID-19) pandemic continues. The aim of this study is to track drug shortages within Illinois and identify causes and trends to this time-sensitive problem. In order to communicate between health systems within the state, the Illinois Council of Health-System Pharmacists (ICHP) developed a medication shortage dashboard, which collects information from health systems in the state on current drug shortages. Classes of medications inquired about included: anti-infectives, neuromuscular blocking agents (NMBAs), sedatives/analgesics, vasopressors, and "others." Data was gathered from 6 different medication shortage dashboards, ranging from May 20, 2020 to June 22, 2020 and was used to track drug shortages within Illinois. Additionally, this data was analyzed in conjunction with the number of hospital beds utilized by COVID-19 patients at the time. Illinois's medication shortage dashboard tracked the supply level of 42 medications used in the treatment of patient's hospitalized with COVID-19. Data from an average of 75 health systems was analyzed each week (average response rate: 52%). For each medication, health systems identified if they had ample supply, mild shortage, moderate shortage, or critical shortage. Overall the trends of these medications positively correlated with the number of hospital beds utilized by COVID-19 patients in Illinois (  = 0.7). The data from this study supports the conclusion that increased hospital bed utilization by COVID-19 patients is correlated with increased drug shortages of medications used in the treatment of COVID-19. It is imperative that health systems take appropriate action to prevent and manage drug shortages.

摘要

随着2019年冠状病毒病(COVID-19)大流行的持续,预计药品短缺情况会随着时间的推移而恶化。本研究的目的是追踪伊利诺伊州内的药品短缺情况,并确定这一具有时间敏感性问题的原因和趋势。为了在该州的医疗系统之间进行沟通,伊利诺伊州医疗系统药剂师理事会(ICHP)开发了一个药品短缺仪表盘,该仪表盘收集该州医疗系统关于当前药品短缺的信息。所询问的药品类别包括:抗感染药、神经肌肉阻滞剂(NMBAs)、镇静剂/镇痛药、血管加压药和“其他”。数据收集自6个不同的药品短缺仪表盘,时间跨度为2020年5月20日至2020年6月22日,并用于追踪伊利诺伊州内的药品短缺情况。此外,该数据还与当时COVID-19患者使用的医院病床数量结合进行了分析。伊利诺伊州的药品短缺仪表盘追踪了用于治疗COVID-19住院患者的42种药品的供应水平。每周平均分析来自75个医疗系统的数据(平均回复率:52%)。对于每种药品,医疗系统确定它们是否有充足供应、轻度短缺、中度短缺或严重短缺。总体而言,这些药品的趋势与伊利诺伊州COVID-19患者使用的医院病床数量呈正相关( = 0.7)。本研究的数据支持这样的结论,即COVID-19患者医院病床使用率的增加与治疗COVID-19所用药品短缺的增加相关。医疗系统必须采取适当行动来预防和管理药品短缺。