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急性视力丧失和结膜出血作为儿童多系统炎症综合征-短暂性症状的明显症状。

Acute Vision Loss and Conjunctival Hemorrhage as Telltale Symptoms of PIMS-TS.

作者信息

Nassih Houda, Belghmaidi Sara, El Qadiry Rabiy, Hajji Ibtissam, Bourrahouat Aicha, Moutaouakil Abdeljalil, Ait Sab Imane

机构信息

Caddy Ayad University, Marrakesh, Morocco.

出版信息

Glob Pediatr Health. 2022 Jul 22;9:2333794X221108727. doi: 10.1177/2333794X221108727. eCollection 2022.

DOI:10.1177/2333794X221108727
PMID:35898321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9310207/
Abstract

There is a global concern about children presenting with inflammatory syndrome with variable clinical features during the ongoing COVID-19 pandemic. This paper reports the first pediatric case of bilateral serous retinal detachment and conjunctival hemorrhage as a revealing pattern of the pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Despite the severity of multisystemic involvement, the management with steroids was very successful. Complete remission was obtained within 3 months of acute onset.

摘要

在当前的新冠疫情期间,儿童出现具有多种临床特征的炎症综合征引起了全球关注。本文报告了首例双侧浆液性视网膜脱离和结膜出血的儿科病例,这是儿童炎症性多系统综合征(PIMS-TS)的一种表现形式,该综合征与严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在时间上相关。尽管多系统受累严重,但使用类固醇治疗非常成功。在急性发作后3个月内实现了完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/c3ce36d5584a/10.1177_2333794X221108727-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/858b21e07cb6/10.1177_2333794X221108727-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/f520ce3af5c7/10.1177_2333794X221108727-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/c3ce36d5584a/10.1177_2333794X221108727-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/858b21e07cb6/10.1177_2333794X221108727-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/f520ce3af5c7/10.1177_2333794X221108727-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a1/9310207/c3ce36d5584a/10.1177_2333794X221108727-fig3.jpg

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本文引用的文献

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Acute kidney injury in children with COVID-19: a retrospective study.儿童 COVID-19 相关急性肾损伤:一项回顾性研究。
BMC Nephrol. 2021 May 31;22(1):202. doi: 10.1186/s12882-021-02389-9.
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Critical analysis of acute kidney injury in pediatric COVID-19 patients in the intensive care unit.对 ICU 中儿科 COVID-19 患者急性肾损伤的批判性分析。
Pediatr Nephrol. 2021 Sep;36(9):2627-2638. doi: 10.1007/s00467-021-05084-x. Epub 2021 Apr 29.
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COVID-19 Associated Multisystem Inflammatory Syndrome: A Systematic Review and Meta-analysis.
COVID-19 相关的多系统炎症综合征:系统评价和荟萃分析。
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):570-588. doi: 10.18502/ijaai.v19i6.4927.
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Distinguishing between typical Kawasaki disease and multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2.区分川崎病和与 SARS-CoV-2 相关的儿童多系统炎症综合征(MIS-C)。
Med Hypotheses. 2020 Nov;144:110263. doi: 10.1016/j.mehy.2020.110263. Epub 2020 Sep 9.
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Kidney Biopsy Findings in Patients With COVID-19, Kidney Injury, and Proteinuria.新型冠状病毒肺炎、肾损伤和蛋白尿患者的肾活检结果
Am J Kidney Dis. 2021 Mar;77(3):465-468. doi: 10.1053/j.ajkd.2020.11.002. Epub 2020 Nov 18.
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COVID-19-Associated Glomerular Disease.COVID-19 相关肾小球疾病。
J Am Soc Nephrol. 2021 Jan;32(1):33-40. doi: 10.1681/ASN.2020060804. Epub 2020 Nov 19.
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Kidney involvement in COVID-19 and its treatments.COVID-19 相关的肾脏损伤及其治疗。
J Med Virol. 2021 Mar;93(3):1387-1395. doi: 10.1002/jmv.26653. Epub 2020 Nov 22.
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COVID-19: In the Eye of the Cytokine Storm.COVID-19:细胞因子风暴眼中的新冠病毒。
Front Immunol. 2020 Sep 24;11:558898. doi: 10.3389/fimmu.2020.558898. eCollection 2020.
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Acute Kidney Injury in Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus-2 Pandemic: Experience From PICUs Across United Kingdom.儿童炎症性多系统综合征伴严重急性呼吸综合征冠状病毒 2 流行的急性肾损伤:英国儿科重症监护病房的经验。
Crit Care Med. 2020 Dec;48(12):1809-1818. doi: 10.1097/CCM.0000000000004662.
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