de Souza J J, Perlmann T, Herman A A, Ransome O J, Kantor R W
S Afr Med J. 1987 Jun 6;71(11):690-2.
The value of maternal C-reactive protein (CRP) levels as predictors of fetal and maternal infective morbidity and fetal mortality was assessed prospectively over a 6-month period in all cases of premature rupture of the fetal membranes or suspected premature labour. Statistical analysis of results showed that CRP at a level of 1.32 mg/dl is a sensitive marker of infective morbidity in mother and neonate. Furthermore, there was a significant association between raised CRP levels and low-birth-weight babies, suggesting that intra-uterine infection is a major cause of prematurity in the study population.
在胎膜早破或疑似早产的所有病例中，前瞻性评估了孕母C反应蛋白（CRP）水平作为胎儿和孕母感染性发病及胎儿死亡预测指标的价值，为期6个月。结果的统计分析表明，CRP水平为1.32mg/dl是母亲和新生儿感染性发病的敏感标志物。此外，CRP水平升高与低体重儿之间存在显著关联，这表明宫内感染是研究人群中早产的主要原因。
