Hajra Adrija, Torrado Juan, Alviar Carlos L, Bangalore Sripal, Keller Norma, Faillace Robert, Sokol Seth
Department of Internal Medicine, New York City Health and Hospitals-Jacobi Medical Center, New York, NY, USA.
Department of Cardiology, New York City Health and Hospitals-Bellevue, New York, NY, USA.
SAGE Open Med Case Rep. 2022 Jul 22;10:2050313X221113934. doi: 10.1177/2050313X221113934. eCollection 2022.
Hypercoagulability in coronavirus disease 2019 infection is already a known fact. But in this article, we have discussed a unique case where the patient had suffered from relapsing thrombus formation. This report describes the case of a patient who presented with chronic coronavirus disease 2019-induced recurrent thrombi refractory to multiple antithrombotic regimens because of multiple recurrent inflammatory flares without any evidence of chronic persistent viral infection. The patient was treated with anticoagulation and anti-inflammatory medications. Still, he had repeated episodes of right ventricular thrombus. Coronavirus disease 2019 can provoke a severe relapsing hypercoagulable state without evidence of persisting viral infection. Rebound inflammatory flares rather than viral recurrence may play a trigger.
新型冠状病毒肺炎感染中的高凝状态已是一个已知事实。但在本文中，我们讨论了一个独特病例，该患者反复出现血栓形成。本报告描述了一名新型冠状病毒肺炎慢性感染患者的病例，该患者因多次反复出现炎症发作而对多种抗血栓治疗方案难治，出现复发性血栓，且无任何慢性持续性病毒感染的证据。该患者接受了抗凝和抗炎药物治疗。然而，他仍反复出现右心室血栓。新型冠状病毒肺炎可引发严重的复发性高凝状态，而无持续病毒感染的证据。反弹性炎症发作而非病毒复发可能起了触发作用。
