Hosseinnejad Seyedeh-Zeynab, Elyasi Forouzan, Mousavinasab Seyed-Nouraddin, Shahhosseini Zohreh
Sexual and Reproductive Health Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Psychiatry and Behavioral Sciences Research Center, Addiction Institute, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Obstet Gynecol Sci. 2022 Sep;65(5):441-450. doi: 10.5468/ogs.22080. Epub 2022 Jul 28.
This study aimed to determine the effect of a support program on burden of spouses caring for their partners with breast cancer.
This randomized controlled trial was conducted among spouses of women with breast cancer undergoing chemotherapy at a referral chemotherapy center in Iran. They were assigned to intervention (n=40) and control (n=40) groups using permuted block randomization. Three small group sessions lasted 45-60 minutes, followed by three telephone-based sessions, lasting 15-20 minutes (twice a week). The intervention sessions included defining stress management strategies in different situations: strengthening creativity, optimism, and management in planning, and defining the role of the caregiver. Primary outcome was care burden, and secondary outcomes were spouses' stress, satisfaction with intervention, and partners' quality of life (QOL). The caregiver burden inventory, depression anxiety stress questionnaire, World Health Organization QOL brief version, and client satisfaction questionnaire were completed before and after the intervention and at a 6-week follow-up.
Thirty-eight participants in each group with a mean age of 44.24±9.01 years completed the study. Repeated measures analysis of variance showed a significant difference in the care burden (P<0.05; effect size, 0.70), stress (P<0.05; effect size, 0.64), and women's QOL (P<0.05; effect size, 0.67) before and after the intervention.
The results of this study can be used to develop interventions, targeting the care burden and stress of spouses of women with breast cancer undergoing chemotherapy.
本研究旨在确定一项支持计划对乳腺癌患者配偶照顾负担的影响。
本随机对照试验在伊朗一家转诊化疗中心对正在接受化疗的乳腺癌女性患者的配偶中进行。采用排列分组随机化将他们分为干预组（n = 40）和对照组（n = 40）。三次小组会议持续45 - 60分钟，随后是三次电话会议，每次持续15 - 20分钟（每周两次）。干预会议包括确定在不同情况下的压力管理策略：增强创造力、乐观态度以及规划管理能力，并明确照顾者的角色。主要结局是照顾负担，次要结局是配偶的压力、对干预的满意度以及伴侣的生活质量（QOL）。在干预前后以及6周随访时完成照顾者负担量表、抑郁焦虑压力问卷、世界卫生组织生活质量简表以及客户满意度问卷。
每组38名平均年龄为44.24±9.01岁的参与者完成了研究。重复测量方差分析显示，干预前后在照顾负担（P<0.05；效应量，0.70）、压力（P<0.05；效应量，0.64）以及女性生活质量（P<0.05；效应量，0.67）方面存在显著差异。
本研究结果可用于制定针对正在接受化疗的乳腺癌女性患者配偶的照顾负担和压力的干预措施。
