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原始与改良远端脾肾分流术的临床比较。

Clinical comparison between original and modified distal splenorenal shunts.

作者信息

Nagasue N, Ogawa Y, Yukaya H, Chang Y C, Nakamura T

出版信息

Surgery. 1987 Jun;101(6):661-7.

PMID:3589962
Abstract

This article reports on a retrospective clinical comparison between the original Warren shunt and one that we modified with Gore-Tex (expanded polytetrafluoroethylene) interposition. The former operation was performed on 35 patients between June 1969 and November 1983 and the latter on 29 patients between October 1983 and January 1986. There were no significant differences in the patients' backgrounds between the two study groups. Blood loss during surgery was significantly greater and operation time was longer in the original shunt group than in the modified shunt group. The incidence of postoperative morbidity and mortality was also significantly higher in the former group than in the latter (major complication rate: 20.0% versus 3.4%; operative death within 1 month: 5.7% versus 0%; in-hospital death: 11.4% versus 3.4%). The modified shunts had a 100% patency rate, and no variceal bleeding was evident, whereas shunt occlusion was observed in two patients and portal thrombosis in one patient of the original shunt group. The incidence of hepatic encephalopathy was 14.3% in the original shunt group and 6.9% in the modified shunt group, and the follow-up time was shorter in the latter group. A significantly greater rate of survival was achieved with the modified Warren shunts. Thus the current study seems to indicate that our modifications could be alternatives to the original distal splenorenal shunt in terms of postoperative morbidity, mortality, and survival.

摘要

本文报道了对原始的沃伦分流术与我们用戈尔特斯(膨体聚四氟乙烯)置入改良的分流术进行的回顾性临床比较。前一种手术于1969年6月至1983年11月期间对35例患者实施,后一种手术于1983年10月至1986年1月期间对29例患者实施。两个研究组患者的背景无显著差异。原始分流术组手术中的失血量显著多于改良分流术组,手术时间也更长。前一组术后发病率和死亡率也显著高于后一组(主要并发症发生率:20.0%对3.4%;1个月内手术死亡:5.7%对0%;住院死亡:11.4%对3.4%)。改良分流术的通畅率为100%,未见静脉曲张出血,而原始分流术组有2例患者出现分流闭塞,1例患者出现门静脉血栓形成。原始分流术组肝性脑病的发生率为14.3%,改良分流术组为6.9%,且后一组的随访时间较短。改良的沃伦分流术实现了显著更高的生存率。因此,目前的研究似乎表明,就术后发病率、死亡率和生存率而言,我们的改良术可作为原始远端脾肾分流术的替代方法。

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