Solakov P Ts, Atanasov N A, Karastanev I I, Kereziev I K, Kuzmanova S I
Ter Arkh. 1987;59(4):20-2.
Uric acid concentration in the serum was investigated 3 times a day using the uricase method in 15 gout inpatients on a hypopurine diet with age- and sex-adjusted caloric content. The highest uric acid concentration was noted at 7 a. m., the lowest concentration value at 11 p. m. The highest renal clearance values were noted from 7 a. m. till 3 p. m., the lowest ones from 11 p. m. till 7 a. m. Similar regularities were noted in 15 rheumatoid arthritic patients, however uric acid concentration in the serum was lower and its renal excretion was 1.7 times more effective.
采用尿酸酶法，对15名采用低嘌呤饮食且热量根据年龄和性别进行调整的痛风住院患者，每天检测3次血清尿酸浓度。上午7点时血清尿酸浓度最高，晚上11点时浓度值最低。上午7点至下午3点肾清除率最高，晚上11点至上午7点最低。15名类风湿关节炎患者也呈现出类似规律，不过其血清尿酸浓度较低，肾脏排泄效率高出1.7倍。
