• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

预测 COVID-19 大流行期间长期抑郁轨迹的因素:四项英国队列的纵向研究。

Predictors of longer-term depression trajectories during the COVID-19 pandemic: a longitudinal study in four UK cohorts.

机构信息

School of Psychology, Centre for Innovation in Mental Health, University of Southampton, Southampton, UK.

Academic Unit of Psychology and Clinical and Experimental Sciences (CNS and Psychiatry), University of Southampton, Southampton, UK.

出版信息

Evid Based Ment Health. 2022 Nov;25(4):e3. doi: 10.1136/ebmental-2022-300461. Epub 2022 Jul 28.

DOI:10.1136/ebmental-2022-300461
PMID:35902216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10231611/
Abstract

BACKGROUND

The COVID-19 pandemic has caused an increase in mental ill health compared with prepandemic levels. Longer-term trajectories of depression in adults during the pandemic remain unclear.

OBJECTIVE

We used latent growth curve modelling to examine individual trajectories of depression symptoms, and their predictors, beyond the early stage of the pandemic.

METHODS

Data were collected in three waves in May 2020, September/October 2020 and February/March 2021 in four UK cohorts (Millennium Cohort Study, Next Steps cohort, British Cohort and National Child Development Study). We included n=16 978 participants (mean age at baseline: 20, 30, 50 and 62, respectively). Self-reported depressive symptoms were the study outcome.

FINDINGS

Symptoms of depression were higher in younger compared with older age groups (d=0.7) across all waves. While depressive symptoms remained stable from May 2020 to Autumn 2020 overall (standardized mean difference (SMD)=0.03, 95% CI 0.02 to 0.04), they increased in all age groups from May 2020 to Spring 2021 (SMD=0.12, 95% CI 0.11 to 0.13). Feelings of loneliness were the strongest predictor and concurrent correlate of increasing depressive symptoms across all cohorts, prepandemic mental health problems and having a long-term illness were also significantly associated with an increase in depression symptoms across all ages. By contrast, compliance with social distancing measures did not predict an increase in depression symptoms.

CONCLUSIONS

Feeling lonely and isolated had a large effect on depression trajectories across all generations, while social distancing measures did not.

CLINICAL IMPLICATIONS

These findings highlight the importance of fostering the feeling of connectedness during COVID-19-related distancing measures.

摘要

背景

与大流行前水平相比,COVID-19 大流行导致精神健康不良的情况有所增加。大流行期间成年人抑郁症的长期轨迹仍不清楚。

目的

我们使用潜在增长曲线模型来检查大流行早期之后抑郁症状的个体轨迹及其预测因素。

方法

在 2020 年 5 月、2020 年 9 月/10 月和 2021 年 2 月/3 月的三个阶段,在英国的四个队列(千禧年队列研究、下一步队列、英国队列和全国儿童发展研究)中收集数据。我们纳入了 n=16978 名参与者(基线时的平均年龄分别为 20、30、50 和 62 岁)。自我报告的抑郁症状是研究结果。

发现

在所有阶段,年轻组的抑郁症状均高于年长组(d=0.7)。尽管整体而言,从 2020 年 5 月到秋季 2020 年,抑郁症状保持稳定(标准化均数差(SMD)=0.03,95%CI 0.02 至 0.04),但在所有年龄组中,从 2020 年 5 月到 2021 年春季,抑郁症状均有所增加(SMD=0.12,95%CI 0.11 至 0.13)。孤独感是所有队列中抑郁症状增加的最强预测因素和同时的相关因素,大流行前的心理健康问题和长期患病也与所有年龄段的抑郁症状增加显著相关。相比之下,遵守社交距离措施并不能预测抑郁症状的增加。

结论

孤独感和孤立感对所有年龄段的抑郁轨迹都有很大影响,而社交距离措施没有。

临床意义

这些发现强调了在 COVID-19 相关隔离措施期间促进联系感的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e46/10231611/2e84922522d2/ebmental-2022-300461f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e46/10231611/2e84922522d2/ebmental-2022-300461f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e46/10231611/2e84922522d2/ebmental-2022-300461f01.jpg

相似文献

1
Predictors of longer-term depression trajectories during the COVID-19 pandemic: a longitudinal study in four UK cohorts.预测 COVID-19 大流行期间长期抑郁轨迹的因素:四项英国队列的纵向研究。
Evid Based Ment Health. 2022 Nov;25(4):e3. doi: 10.1136/ebmental-2022-300461. Epub 2022 Jul 28.
2
Psychological Distress Before and During the COVID-19 Pandemic Among Adults in the United Kingdom Based on Coordinated Analyses of 11 Longitudinal Studies.基于 11 项纵向研究的协调分析,英国成年人在 COVID-19 大流行前后的心理困扰。
JAMA Netw Open. 2022 Apr 1;5(4):e227629. doi: 10.1001/jamanetworkopen.2022.7629.
3
Long-term psychological distress trajectories and the COVID-19 pandemic in three British birth cohorts: A multi-cohort study.长期心理困扰轨迹与三个人群队列中的 COVID-19 大流行:一项多人群队列研究。
PLoS Med. 2023 Apr 4;20(4):e1004145. doi: 10.1371/journal.pmed.1004145. eCollection 2023 Apr.
4
Trajectories of depression and anxiety symptoms during the COVID-19 pandemic in a representative Australian adult cohort.COVID-19大流行期间澳大利亚具有代表性的成年队列中抑郁和焦虑症状的轨迹
Med J Aust. 2021 Jun;214(10):462-468. doi: 10.5694/mja2.51043. Epub 2021 Apr 26.
5
Investigating the relationship of COVID-19 related stress and media consumption with schizotypy, depression, and anxiety in cross-sectional surveys repeated throughout the pandemic in Germany and the UK.调查德国和英国在整个大流行期间通过横断面调查重复进行的 COVID-19 相关压力和媒体消费与精神分裂症倾向、抑郁和焦虑之间的关系。
Elife. 2022 Jul 4;11:e75893. doi: 10.7554/eLife.75893.
6
Trajectories of anxiety and depressive symptoms during enforced isolation due to COVID-19 in England: a longitudinal observational study.因 COVID-19 而在英国强制隔离期间焦虑和抑郁症状的轨迹:一项纵向观察研究。
Lancet Psychiatry. 2021 Feb;8(2):141-149. doi: 10.1016/S2215-0366(20)30482-X. Epub 2020 Dec 9.
7
Mental health in the UK during the COVID-19 pandemic: cross-sectional analyses from a community cohort study.新冠疫情期间英国的心理健康状况:一项社区队列研究的横断面分析
BMJ Open. 2020 Sep 15;10(9):e040620. doi: 10.1136/bmjopen-2020-040620.
8
The role of pre-pandemic depression for changes in depression, anxiety, and loneliness during the COVID-19 pandemic: Results from a longitudinal probability sample of adults from Germany.新冠疫情前的抑郁对COVID-19大流行期间抑郁、焦虑和孤独感变化的作用:来自德国成年人纵向概率样本的结果
Eur Psychiatry. 2022 Nov 3;65(1):e76. doi: 10.1192/j.eurpsy.2022.2339.
9
Depressive and anxiety symptoms in adults during the COVID-19 pandemic in England: A panel data analysis over 2 years.英格兰 COVID-19 大流行期间成年人的抑郁和焦虑症状:长达 2 年的面板数据分析。
PLoS Med. 2023 Apr 18;20(4):e1004144. doi: 10.1371/journal.pmed.1004144. eCollection 2023 Apr.
10
Heterogeneity in depressive and anxiety symptoms and loneliness during the COVID-19 pandemic: Results from three Dutch psychiatric case-control cohorts from April 2020 to February 2022.新冠大流行期间抑郁和焦虑症状及孤独的异质性:来自 2020 年 4 月至 2022 年 2 月荷兰三个精神病学病例对照队列的结果。
J Psychosom Res. 2023 Feb;165:111138. doi: 10.1016/j.jpsychores.2022.111138. Epub 2022 Dec 26.

引用本文的文献

1
Associations between exercise patterns and health outcomes in sedentary and non-sedentary individuals: a longitudinal population-based study in Geneva, Switzerland.久坐和非久坐个体的运动模式与健康结果之间的关联:瑞士日内瓦一项基于人群的纵向研究
BMJ Public Health. 2025 Aug 10;3(2):e001745. doi: 10.1136/bmjph-2024-001745. eCollection 2025.
2
Exploring depression in adults over a decade: a review of longitudinal studies.十年间成人抑郁症研究综述:纵向研究回顾
BMC Psychiatry. 2025 Apr 15;25(1):378. doi: 10.1186/s12888-025-06828-x.
3
Depressive Symptom Change Patterns during the COVID-19 Pandemic and Their Impact on Psychiatric Treatment Seeking: A 24-Month Observational Study of the Adult Population.

本文引用的文献

1
Immediate and Longer-Term Changes in the Mental Health and Well-being of Older Adults in England During the COVID-19 Pandemic.英格兰 COVID-19 大流行期间老年人心理健康和幸福感的即时和长期变化。
JAMA Psychiatry. 2022 Feb 1;79(2):151-159. doi: 10.1001/jamapsychiatry.2021.3749.
2
A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020.2020 年新冠肺炎大流行前后的纵向队列研究的系统评价和荟萃分析比较心理健康。
J Affect Disord. 2022 Jan 1;296:567-576. doi: 10.1016/j.jad.2021.09.098. Epub 2021 Oct 1.
3
Longitudinal analysis of the UK COVID-19 Psychological Wellbeing Study: Trajectories of anxiety, depression and COVID-19-related stress symptomology.
新冠疫情期间抑郁症状变化模式及其对寻求精神科治疗的影响:一项针对成年人群的24个月观察性研究
Depress Anxiety. 2024 Aug 5;2024:1272738. doi: 10.1155/2024/1272738. eCollection 2024.
4
Trajectories of depression and anxiety in adults with rare disorders across 13 months during the COVID-19 pandemic.新冠疫情期间13个月内患有罕见疾病的成年人的抑郁和焦虑轨迹。
Orphanet J Rare Dis. 2025 Mar 20;20(1):138. doi: 10.1186/s13023-025-03633-3.
5
The unequal impacts of the COVID-19 pandemic on young adults' mental health. Predictors of vulnerability and resilience using longitudinal birth cohort data in the UK.新冠疫情对年轻人心理健康的不平等影响。利用英国纵向出生队列数据进行脆弱性和复原力预测因素研究。
J Adolesc. 2025 Jan;97(1):102-112. doi: 10.1002/jad.12400. Epub 2024 Aug 29.
6
Depressive and anxiety symptoms in the course of the COVID-19 pandemic among physicians in hospitals: results of the longitudinal, multicenter VOICE-EgePan survey over two years.在 COVID-19 大流行期间,医院医生的抑郁和焦虑症状:跨两年的纵向、多中心 VOICE-EgePan 调查结果。
BMC Psychol. 2023 Oct 10;11(1):327. doi: 10.1186/s40359-023-01354-5.
7
Changes on depression and suicidal ideation under severe lockdown restrictions during the first wave of the COVID-19 pandemic in Spain: a longitudinal study in the general population.在西班牙 COVID-19 大流行第一波期间的严格封锁限制下,抑郁和自杀意念的变化:一般人群中的纵向研究。
Epidemiol Psychiatr Sci. 2023 Sep 1;32:e55. doi: 10.1017/S2045796023000677.
8
Benefits of Working from Home During the COVID-19 Pandemic for Undiagnosed Workers with Attention-Deficit/Hyperactivity Disorder Symptoms.新冠疫情期间,对有注意力缺陷多动障碍症状但未确诊的工作者而言居家办公的益处。
Neuropsychiatr Dis Treat. 2023 Jul 15;19:1607-1621. doi: 10.2147/NDT.S414862. eCollection 2023.
9
Heterogeneous Mental Health Responses to the COVID-19 Pandemic in Germany: An Examination of Long-Term Trajectories, Risk Factors, and Vulnerable Groups.德国对新冠疫情的异质性心理健康反应:长期轨迹、风险因素及弱势群体研究
Healthcare (Basel). 2023 May 3;11(9):1305. doi: 10.3390/healthcare11091305.
10
Depression, anxiety, and suicidal ideation in a population-based cohort of young adults before and during the first 12 months of the COVID-19 pandemic in Canada.在加拿大 COVID-19 大流行的前 12 个月和期间,对基于人群的年轻成年人队列进行的抑郁、焦虑和自杀意念研究。
Can J Public Health. 2023 Jun;114(3):368-377. doi: 10.17269/s41997-023-00772-7. Epub 2023 Apr 24.
纵向分析英国 COVID-19 心理健康研究:焦虑、抑郁和 COVID-19 相关应激症状的轨迹。
Psychiatry Res. 2021 Oct;304:114138. doi: 10.1016/j.psychres.2021.114138. Epub 2021 Jul 25.
4
Mental health responses to the COVID-19 pandemic: a latent class trajectory analysis using longitudinal UK data.心理健康对 COVID-19 大流行的反应:使用英国纵向数据的潜在类别轨迹分析。
Lancet Psychiatry. 2021 Jul;8(7):610-619. doi: 10.1016/S2215-0366(21)00151-6. Epub 2021 May 6.
5
Inequality-Related Health and Social Factors and Their Impact on Well-Being during the COVID-19 Pandemic: Findings from a National Survey in the UK.不平等相关的健康和社会因素及其对 COVID-19 大流行期间幸福感的影响:来自英国全国性调查的发现。
Int J Environ Res Public Health. 2021 Jan 24;18(3):1014. doi: 10.3390/ijerph18031014.
6
Social relationships and depression during the COVID-19 lockdown: longitudinal analysis of the COVID-19 Social Study.新冠疫情封锁期间的社会关系与抑郁:新冠疫情社会研究的纵向分析
Psychol Med. 2021 Jan 13:1-10. doi: 10.1017/S0033291721000039.
7
Trajectories of anxiety and depressive symptoms during enforced isolation due to COVID-19 in England: a longitudinal observational study.因 COVID-19 而在英国强制隔离期间焦虑和抑郁症状的轨迹:一项纵向观察研究。
Lancet Psychiatry. 2021 Feb;8(2):141-149. doi: 10.1016/S2215-0366(20)30482-X. Epub 2020 Dec 9.
8
Longitudinal changes in mental health and the COVID-19 pandemic: evidence from the UK Household Longitudinal Study.心理健康的纵向变化与新冠疫情:来自英国家庭纵向研究的证据。
Psychol Med. 2022 Oct;52(13):2549-2558. doi: 10.1017/S0033291720004432. Epub 2020 Nov 13.
9
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA.新冠病毒与精神障碍之间的双向关联:美国 62354 例新冠病毒病例的回顾性队列研究。
Lancet Psychiatry. 2021 Feb;8(2):130-140. doi: 10.1016/S2215-0366(20)30462-4. Epub 2020 Nov 9.
10
Psychological distress and adaptation to the COVID-19 crisis in the United States.美国民众的心理困扰与对新冠危机的适应。
J Psychiatr Res. 2021 Apr;136:603-609. doi: 10.1016/j.jpsychires.2020.10.035. Epub 2020 Oct 27.