Jia Ru, Ayling Kieran, Chalder Trudie, Massey Adam, Broadbent Elizabeth, Coupland Carol, Vedhara Kavita
Division of Primary Care, University of Nottingham, Nottingham, UK.
Psychological Medicine, King's College London, London, UK.
BMJ Open. 2020 Sep 15;10(9):e040620. doi: 10.1136/bmjopen-2020-040620.
Previous pandemics have resulted in significant consequences for mental health. Here, we report the mental health sequelae of the COVID-19 pandemic in a UK cohort and examine modifiable and non-modifiable explanatory factors associated with mental health outcomes. We focus on the first wave of data collection, which examined short-term consequences for mental health, as reported during the first 4-6 weeks of social distancing measures being introduced.
Cross-sectional online survey.
Community cohort study.
N=3097 adults aged ≥18 years were recruited through a mainstream and social media campaign between 3 April 2020 and 30 April 2020. The cohort was predominantly female (n=2618); mean age 44 years; 10% (n=296) from minority ethnic groups; 50% (n=1559) described themselves as key workers and 20% (n=649) identified as having clinical risk factors putting them at increased risk of COVID-19.
Depression, anxiety and stress scores.
Mean scores for depression ([Formula: see text] =7.69, SD=6.0), stress ([Formula: see text] =6.48, SD=3.3) and anxiety ([Formula: see text] = 6.48, SD=3.3) significantly exceeded population norms (all p<0.0001). Analysis of non-modifiable factors hypothesised to be associated with mental health outcomes indicated that being younger, female and in a recognised COVID-19 risk group were associated with increased stress, anxiety and depression, with the final multivariable models accounting for 7%-14% of variance. When adding modifiable factors, significant independent effects emerged for positive mood, perceived loneliness and worry about getting COVID-19 for all outcomes, with the final multivariable models accounting for 54%-57% of total variance.
Increased psychological morbidity was evident in this UK sample and found to be more common in younger people, women and in individuals who identified as being in recognised COVID-19 risk groups. Public health and mental health interventions able to ameliorate perceptions of risk of COVID-19, worry about COVID-19 loneliness and boost positive mood may be effective.
既往的大流行对心理健康产生了重大影响。在此,我们报告了英国一个队列中新冠疫情的心理健康后遗症,并研究了与心理健康结果相关的可改变和不可改变的解释因素。我们关注的是第一波数据收集,该收集调查了在实施社交距离措施的前4至6周内报告的心理健康短期后果。
横断面在线调查。
社区队列研究。
2020年4月3日至2020年4月30日期间,通过主流媒体和社交媒体活动招募了N = 3097名年龄≥18岁的成年人。该队列主要为女性(n = 2618);平均年龄44岁;10%(n = 296)来自少数族裔群体;50%(n = 1559)称自己为关键工作者,20%(n = 649)被确定有临床风险因素,使其感染新冠病毒的风险增加。
抑郁、焦虑和压力评分。
抑郁([公式:见原文] = 7.69,标准差 = 6.0)、压力([公式:见原文] = 6.48,标准差 = 3.3)和焦虑([公式:见原文] = 6.48,标准差 = 3.3)的平均得分显著超过总体标准(所有p < 0.0001)。对假设与心理健康结果相关的不可改变因素的分析表明,年龄较小、女性以及属于公认的新冠病毒风险组与压力、焦虑和抑郁增加有关,最终的多变量模型解释了7% - 14%的方差。加入可改变因素后,积极情绪、感知到的孤独感以及对感染新冠病毒的担忧对所有结果均产生了显著的独立影响,最终的多变量模型解释了总方差的54% - 57%。
在这个英国样本中,心理发病率增加明显,且在年轻人、女性以及被确定属于公认的新冠病毒风险组的个体中更为常见。能够改善对新冠病毒风险的认知、对新冠病毒的担忧、孤独感并提升积极情绪的公共卫生和心理健康干预措施可能会有效。