Mahadevan Preveina, Harley Mia, Fordyce Stuart, Hodgson Susan, Ghosh Rebecca, Myles Puja, Booth Helen, Axson Eleanor
CPRD, Medicines and Healthcare Products Regulatory Agency, London, UK
CPRD, Medicines and Healthcare Products Regulatory Agency, London, UK.
J Epidemiol Community Health. 2022 Jul 28;76(10):880-6. doi: 10.1136/jech-2022-219200.
The Clinical Practice Research Datalink (CPRD) holds primary care electronic healthcare records for 25% of the UK population. CPRD data can be linked via practice postcode in the UK, and additionally via patient postcode in England, to area-level socioeconomic status (SES) data including the Index of Multiple Deprivation (IMD), the Carstairs Index and the Townsend Deprivation Index; as well as rural-urban classification (RUC). This study aims to describe the completeness and representativeness of CPRD-linked SES and RUC data.
Patients currently registered at general practices contributing data to the May 2021 snapshots of CPRD GOLD (n=445 587) and CPRD Aurum (n=13 278 825) were used to assess the completeness and representativeness of CPRD-linked SES and RUC data against the UK general population.
All currently registered patients had complete SES and RUC data at practice level across the UK. Most English patients in CPRD GOLD (78%), CPRD Aurum (94%) and combined (93%) had SES and RUC data at patient level. Patient-level SES data in CPRD for England were comparable to England's general population (average IMD decile in CPRD 5.52±0.00 vs 5.50±0.02). CPRD UK practices were on average in more deprived areas than the UK general population (6.06±0.07 vs 5.50±0.02). A slightly higher proportion of CPRD patients and practices were from urban areas (85%) as compared with the UK general population (82%).
Completeness of CPRD-linked SES and RUC data is high. The CPRD populations were broadly representative of the general populations in the UK in terms of SES and RUC.
临床实践研究数据链（CPRD）拥有英国25%人口的基层医疗电子健康记录。CPRD数据可通过英国的诊所邮政编码，以及英格兰地区患者的邮政编码，与地区层面的社会经济地位（SES）数据相链接，包括多重贫困指数（IMD）、卡斯尔斯指数和汤森贫困指数；以及城乡分类（RUC）。本研究旨在描述与CPRD相链接的SES和RUC数据的完整性和代表性。
使用当前在为CPRD GOLD 2021年5月快照（n = 445587）和CPRD Aurum（n = 13278825）贡献数据的全科诊所注册的患者，来评估与CPRD相链接的SES和RUC数据相对于英国普通人群的完整性和代表性。
英国所有当前注册患者在诊所层面均拥有完整的SES和RUC数据。CPRD GOLD中大多数英格兰患者（78%）、CPRD Aurum中（94%）以及两者合并后（93%）在患者层面拥有SES和RUC数据。CPRD中英格兰患者层面的SES数据与英格兰普通人群相当（CPRD中平均IMD十分位数为5.52±0.00，而普通人群为5.50±0.02）。CPRD英国诊所平均所处地区的贫困程度高于英国普通人群（6.06±0.07对5.50±0.02）。与英国普通人群（82%）相比，CPRD患者和诊所来自城市地区的比例略高（85%）。
与CPRD相链接的SES和RUC数据完整性较高。就SES和RUC而言，CPRD人群在很大程度上代表了英国的普通人群。
