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冲击波的生物学效应:狗体内冲击波所致的肺出血——压力依赖性

Biological effects of shock waves: lung hemorrhage by shock waves in dogs--pressure dependence.

作者信息

Delius M, Enders G, Heine G, Stark J, Remberger K, Brendel W

出版信息

Ultrasound Med Biol. 1987 Feb;13(2):61-7. doi: 10.1016/0301-5629(87)90075-5.

Abstract

The most serious side effect observed during the destruction of gallstones by shock waves in dogs was lung bleeding. To determine the conditions leading to lung damage, pressure probes were implanted into dogs between the lung and the diaphragm. The distance between the lung and the focal point of the pressure field was determined at which 1000 shock waves caused no more lung hemorrhage. On the long axis it is greater than 15 cm and perpendicular to the long axis it is 4 cm. Shock wave pressures over 2 MPa could be administered safely, whereas a pressure of 10 MPa caused bleedings in beagles, but probably not in boxers.

摘要

在犬类中通过冲击波破坏胆结石时观察到的最严重副作用是肺出血。为了确定导致肺损伤的条件,将压力探头植入犬类的肺和横膈膜之间。确定了肺与压力场焦点之间的距离,在该距离下施加1000次冲击波不会再导致肺出血。在长轴上该距离大于15厘米,垂直于长轴时为4厘米。超过2兆帕的冲击波压力可以安全施加,而10兆帕的压力会导致小猎犬出血,但对拳师犬可能不会。

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