Delius M, Jordan M, Eizenhoefer H, Marlinghaus E, Heine G, Liebich H G, Brendel W
Institute for Surgical Research, University of Munich, Federal Republic of Germany.
Ultrasound Med Biol. 1988;14(8):689-94. doi: 10.1016/0301-5629(88)90025-7.
The effect of shock waves on normal canine kidneys was examined in two groups of dogs whose right kidneys were exposed to 3000 shock waves generated with 20 kV and 40 nF in a Dornier HM II lithotripter. The groups differed only in the rate of shock wave administration which was 100 and 1 per second, respectively. Autopsy was performed 24 to 30 h later. Macroscopically and histologically, significantly more haemorrhages occurred in the kidney parenchyma if shock waves were administered at a rate of 100 waves per second. Haemorrhages were diffuse, the outer medulla was most heavily affected. The results show that kidney damage is dependent on the rate of shock wave administration. They argue against a direct shock wave effect and favor cavitation as the mechanism of shock wave damage although thermal effects cannot be excluded.
在两组犬中研究了冲击波对正常犬肾的影响。在多尼尔HM II型碎石机中，用20 kV和40 nF产生3000次冲击波，使两组犬的右肾暴露于这些冲击波中。两组的区别仅在于冲击波施加的速率，分别为每秒100次和每秒1次。24至30小时后进行尸检。从宏观和组织学上看，如果以每秒100次的速率施加冲击波，肾实质内出现的出血明显更多。出血呈弥漫性，外髓质受影响最严重。结果表明，肾损伤取决于冲击波施加的速率。这些结果不支持冲击波的直接作用，而倾向于空化作为冲击波损伤的机制，尽管不能排除热效应。
