Yonamine Sean, Ton Lauren, Rose-Nussbaumer Jennifer, Ying Gui-Shuang, Ahmed Iqbal Ike K, Chen Teresa C, Weiner Asher, Gedde Steven J, Han Ying
Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.
School of Medicine, University of California San Francisco, San Francisco, CA, USA.
Clin Ophthalmol. 2022 Jul 21;16:2305-2310. doi: 10.2147/OPTH.S369673. eCollection 2022.
To assess practice patterns and opinions of glaucoma specialists regarding glaucoma drainage device tube shunt placement and post-operative anti-inflammatory medication use. We also assess the perceived need for a randomized control trial to compare them.
An online survey was distributed to a group of glaucoma specialists from the American Glaucoma Society via the American Glaucoma Society forum from April to August 2021.
One hundred and twenty-eight responses were included. Ninety percent placed tubes in the anterior chamber. Sixty-one percent reported that evidence suggested the superiority of sulcus tube placement over the anterior chamber, whereas 34% reported there was not enough evidence to suggest superiority of either in preventing endothelial cell loss. Comparing these techniques for intraocular pressure control, 49% reported evidence suggested sulcus tube placement superiority whereas 46% reported there was not enough evidence. Over 40% of respondents reported that they were either unfamiliar with literature or that there was not enough evidence to support the superiority of difluprednate 0.05% over prednisolone 1% for post-operative use in preventing endothelial cell loss and for intraocular pressure control. Ninety percent and 81% of respondents respectively would benefit from randomized control trials comparing outcomes of anterior chamber vs sulcus tube placement and post-operative corticosteroid usage.
Most glaucoma specialists surveyed place glaucoma drainage device tube in the anterior chamber over the sulcus. A randomized control trial to determine optimal tube placement and post-operative anti-inflammatory medication use for preventing endothelial cell loss would change current glaucoma drainage device practice patterns.
评估青光眼专家在青光眼引流装置管分流置入及术后抗炎药物使用方面的实践模式和观点。我们还评估了开展一项随机对照试验以比较二者的必要性。
2021年4月至8月,通过美国青光眼协会论坛向一组美国青光眼协会的青光眼专家进行了在线调查。
共纳入128份回复。90%的人将引流管置于前房。61%的人报告称有证据表明巩膜沟置管优于前房置管,而34%的人报告称没有足够证据表明二者在预防内皮细胞丢失方面具有优越性。在比较这些技术对眼压的控制效果时,49%的人报告称有证据表明巩膜沟置管更具优势,而46%的人报告称没有足够证据。超过40%的受访者表示,他们要么不熟悉相关文献,要么没有足够证据支持0.05%的双氟泼尼酯在预防内皮细胞丢失和控制眼压方面优于1%的泼尼松龙用于术后使用。90%和81%的受访者分别认为开展比较前房置管与巩膜沟置管效果以及术后皮质类固醇使用情况的随机对照试验会有所帮助。
大多数接受调查的青光眼专家将青光眼引流装置管置于前房而非巩膜沟。一项旨在确定预防内皮细胞丢失的最佳置管位置和术后抗炎药物使用的随机对照试验将改变当前青光眼引流装置的实践模式。