Šamec Dunja, Loizzo Monica Rosa, Gortzi Olga, Çankaya İrem Tatlı, Tundis Rosa, Suntar İpek, Shirooie Samira, Zengin Gokhan, Devkota Hari Prasad, Reboredo-Rodríguez Patricia, Hassan Sherif T S, Manayi Azadeh, Kashani Hamid Reza Khayat, Nabavi Seyed Mohammad
Department of Food Technology, University Center Koprivnica, University North, Koprivnica, Croatia.
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, CS, Italy.
Compr Rev Food Sci Food Saf. 2022 Sep;21(5):4422-4446. doi: 10.1111/1541-4337.13013. Epub 2022 Jul 29.
The growing interest in foods that can be beneficial to human health is bringing into focus some products that have been used locally for centuries but have recently gained worldwide attention. One of these foods is pumpkin seed oil, which has been used in culinary and traditional medicine, but recent data also show its use in the pharmaceutical and cosmetic industries. In addition, some sources refer to it as a potential functional food, mainly because it is obtained from pumpkin seeds, which contain many functional components. However, the production process of the oil may affect the content of these components and consequently the biological activity of the oil. In this review, we have focused on summarizing scientific data that explore the potential of pumpkin seed oil as a functional food ingredient. We provide a comprehensive overview of pumpkin seed oil chemical composition, phytochemical content, biological activity, and safety, as well as the overview of production processes and contemporary use. The main phytochemicals in pumpkin seed oil with health-related properties are polyphenols, phytoestrogens, and fatty acids, but carotenoids, squalene, tocopherols, and minerals may also contribute to health benefits. Most studies have been conducted in vitro and support the claim that pumpkin seed oil has antioxidant and antimicrobial activities. Clinical studies have shown that pumpkin seed oil may be beneficial in the treatment of cardiovascular problems of menopausal women and ailments associated with imbalance of sex hormones.
人们对有益于人体健康的食物的兴趣日益浓厚，这使得一些在当地使用了几个世纪但最近才受到全球关注的产品成为焦点。其中一种食物就是南瓜籽油，它一直被用于烹饪和传统医学，但最近的数据也显示其在制药和化妆品行业的应用。此外，一些资料将其称为潜在的功能性食品，主要是因为它是从南瓜籽中提取的，而南瓜籽含有许多功能性成分。然而，油的生产过程可能会影响这些成分的含量，进而影响油的生物活性。在这篇综述中，我们着重总结了探索南瓜籽油作为功能性食品成分潜力的科学数据。我们全面概述了南瓜籽油的化学成分、植物化学成分、生物活性和安全性，以及生产过程和当代用途。南瓜籽油中具有健康相关特性的主要植物化学物质是多酚、植物雌激素和脂肪酸，但类胡萝卜素、角鲨烯、生育酚和矿物质也可能对健康有益。大多数研究是在体外进行的，支持了南瓜籽油具有抗氧化和抗菌活性的说法。临床研究表明，南瓜籽油可能有助于治疗绝经后女性的心血管问题以及与性激素失衡相关的疾病。
