Codon-specific interaction of uncharged transfer-RNA with eukaryotic ribosomes.
作者信息
Murchie M J, Leader D P
出版信息
Biochim Biophys Acta. 1978 Aug 23;520(1):233-6. doi: 10.1016/0005-2787(78)90024-2.
PMID:359051
Abstract
Rat liver ribosomes bound [32P]tRNAPhe in both a codon-dependent and codon-independent manner. The codon-dependent binding was studied further by utilising the ability of the unchanged tRNAPhe to inhibit the poly(U)-directed binding of [3H]Phe-tRNA to ribosomes. At least part of the codon-dependent binding of uncharged tRNA appears to be to the ribosomal A-site.
摘要
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