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转移性乳腺癌继发急性阑尾炎。首次原发性肿瘤诊断12年后。病例报告。

Acute appendicitis secondary to metastatic breast cancer. 12 Years after first primary tumor diagnosis. A case report.

作者信息

Hughes Victoria G, Osácar Pedro, Ramallo Darío

机构信息

Department of Surgery, Hospital Interzonal General de Agudos San Roque of Gonnet, Buenos Aires, Argentina.

Department of Surgery, Hospital Interzonal General de Agudos San Roque of Gonnet, Buenos Aires, Argentina.

出版信息

Int J Surg Case Rep. 2022 Aug;97:107452. doi: 10.1016/j.ijscr.2022.107452. Epub 2022 Jul 25.

Abstract

INTRODUCTION

Metastatic adenocarcinoma to the appendix is an uncommon finding, there are few published cases in the literature of appendicitis from metastatic breast carcinoma.

PRESENTATION OF CASE

A 51-year-old female was admitted to the emergency department with a presumptive diagnosis of acute appendicitis with a past medical history of stage IV Breast Cancer 12 years ago. Appendectomy was performed, finding a perforated appendix. Anatomo-pathology examination revealed a semi-differentiated carcinoma involving the tip of the appendix.

DISCUSSION

Gastrointestinal tract (GIT) metastases of breast carcinoma are an uncommon finding. Appendiceal metastases are a very uncommon finding, and the interval between diagnosis of the primary carcinoma and the metastases can be many years. There are no reports about whether right hemicolectomy provides better oncological outcomes than an appendectomy in stage IV BC.

CONCLUSION

There are no guidelines for the management of this disease but unquestionably, multidisciplinary management leads to better outcomes.

摘要

引言

转移性腺癌累及阑尾是一种罕见的情况,文献中关于转移性乳腺癌导致阑尾炎的病例报道很少。

病例介绍

一名51岁女性因疑似急性阑尾炎入院,她有12年前IV期乳腺癌的既往病史。进行了阑尾切除术,发现阑尾穿孔。解剖病理学检查显示阑尾尖端有半分化癌。

讨论

乳腺癌的胃肠道转移是一种罕见的情况。阑尾转移非常罕见,原发癌诊断与转移之间的间隔可能长达数年。对于IV期乳腺癌患者,右半结肠切除术是否比阑尾切除术能带来更好的肿瘤学结局,尚无相关报道。

结论

对于这种疾病的管理尚无指南,但毫无疑问,多学科管理会带来更好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f615/9403286/5645831a322e/gr1.jpg

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