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乳腺癌阑尾转移:一例报告及文献综述

Appendiceal Metastasis of Breast Cancer: A Case Report and a Literature Review.

作者信息

Yagyu Takuki, Miki Hisanori, Kikawa Yuichiro, Kobayashi Toshinori, Sekimoto Mitsugu

机构信息

Department of Surgery, Kansai Medical University, Hirakata, JPN.

出版信息

Cureus. 2024 Apr 9;16(4):e57929. doi: 10.7759/cureus.57929. eCollection 2024 Apr.

DOI:10.7759/cureus.57929
PMID:38725791
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11081716/
Abstract

Appendiceal metastases of breast cancer (BC) are very rare, and there are few reports of resection. Asymptomatic appendiceal enlargement is often suspected to be a primary appendiceal tumor, making it difficult to suspect metastatic tumors, especially metastases from BC. On the other hand, advances in drug therapy, including hormonal therapy for BC, have prolonged survival, and there is a possibility of encountering metastatic cases that have rarely been seen before. We herein present a case in which an enlarged appendix, identified during hormonal therapy for advanced BC, was laparoscopically removed and diagnosed as BC metastasis. A 53-year-old woman had been diagnosed with invasive ductal carcinoma (IDC) based on a breast biopsy, and the appendiceal specimen was diagnosed as invasive lobular carcinoma (ILC). We herein report this unique case and provide a detailed review of 13 previous reports.

摘要

乳腺癌(BC)的阑尾转移非常罕见,关于阑尾转移癌切除术的报道很少。无症状的阑尾肿大常被怀疑是原发性阑尾肿瘤,很难怀疑是转移性肿瘤,尤其是来自乳腺癌的转移。另一方面,包括乳腺癌激素治疗在内的药物治疗进展延长了患者生存期,有可能遇到以前很少见的转移病例。在此,我们报告一例在晚期乳腺癌激素治疗期间发现阑尾肿大,经腹腔镜切除并诊断为乳腺癌转移的病例。一名53岁女性经乳腺活检被诊断为浸润性导管癌(IDC),阑尾标本被诊断为浸润性小叶癌(ILC)。我们在此报告这一独特病例,并对之前的13篇报道进行详细综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/ae52f3adb3d1/cureus-0016-00000057929-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/df5d5b3fa28a/cureus-0016-00000057929-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/0acb7f7f2f75/cureus-0016-00000057929-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/ae52f3adb3d1/cureus-0016-00000057929-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/df5d5b3fa28a/cureus-0016-00000057929-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/0acb7f7f2f75/cureus-0016-00000057929-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01e8/11081716/ae52f3adb3d1/cureus-0016-00000057929-i03.jpg

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本文引用的文献

1
Metastatic Breast Cancer Presenting as Acute Appendicitis: A Rare Case Study and Review of Current Knowledge.以急性阑尾炎表现的转移性乳腺癌:一例罕见病例研究及当前知识综述
Diagnostics (Basel). 2023 Dec 13;13(24):3657. doi: 10.3390/diagnostics13243657.
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Appendiceal neoplasms-A practical guide.阑尾肿瘤——实用指南。
J Surg Oncol. 2023 Jun;127(8):1300-1305. doi: 10.1002/jso.27304.
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Metastatic Breast Cancer Presenting as Acute Appendicitis.以急性阑尾炎表现的转移性乳腺癌
Cureus. 2022 Oct 19;14(10):e30456. doi: 10.7759/cureus.30456. eCollection 2022 Oct.
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Gastrointestinal Tract Metastases of Invasive Lobular Carcinoma of the Breast: An Immunohistochemical Survey Algorithm.乳腺浸润性小叶癌的胃肠道转移:一种免疫组织化学检测算法
Eur J Breast Health. 2022 Oct 1;18(4):375-380. doi: 10.4274/ejbh.galenos.2022.2022-1-5. eCollection 2022 Oct.
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Acute appendicitis secondary to metastatic breast cancer. 12 Years after first primary tumor diagnosis. A case report.转移性乳腺癌继发急性阑尾炎。首次原发性肿瘤诊断12年后。病例报告。
Int J Surg Case Rep. 2022 Aug;97:107452. doi: 10.1016/j.ijscr.2022.107452. Epub 2022 Jul 25.
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Colonic Metastasis from Breast Cancer: A Case Report and Review of the Literature.乳腺癌结肠转移:病例报告及文献复习。
In Vivo. 2022 Jan-Feb;36(1):522-527. doi: 10.21873/invivo.12733.
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Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
8
Acute appendicitis as an unusual cause of invasive ductal breast carcinoma metastasis.急性阑尾炎作为浸润性导管癌转移的罕见原因。
J Surg Case Rep. 2020 Dec 28;2020(12):rjaa535. doi: 10.1093/jscr/rjaa535. eCollection 2020 Dec.
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Acute Appendicitis and Small Bowel Obstruction Secondary to Metastatic Breast Cancer.转移性乳腺癌继发急性阑尾炎和小肠梗阻
Cureus. 2019 May 21;11(5):e4706. doi: 10.7759/cureus.4706.
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Right hemicolectomy for acute appendicitis secondary to breast cancer metastases.因乳腺癌转移继发急性阑尾炎而行右半结肠切除术。
Singapore Med J. 2018 May;59(5):284-285. doi: 10.11622/smedj.2018061.