Yagyu Takuki, Miki Hisanori, Kikawa Yuichiro, Kobayashi Toshinori, Sekimoto Mitsugu
Department of Surgery, Kansai Medical University, Hirakata, JPN.
Cureus. 2024 Apr 9;16(4):e57929. doi: 10.7759/cureus.57929. eCollection 2024 Apr.
Appendiceal metastases of breast cancer (BC) are very rare, and there are few reports of resection. Asymptomatic appendiceal enlargement is often suspected to be a primary appendiceal tumor, making it difficult to suspect metastatic tumors, especially metastases from BC. On the other hand, advances in drug therapy, including hormonal therapy for BC, have prolonged survival, and there is a possibility of encountering metastatic cases that have rarely been seen before. We herein present a case in which an enlarged appendix, identified during hormonal therapy for advanced BC, was laparoscopically removed and diagnosed as BC metastasis. A 53-year-old woman had been diagnosed with invasive ductal carcinoma (IDC) based on a breast biopsy, and the appendiceal specimen was diagnosed as invasive lobular carcinoma (ILC). We herein report this unique case and provide a detailed review of 13 previous reports.
乳腺癌(BC)的阑尾转移非常罕见,关于阑尾转移癌切除术的报道很少。无症状的阑尾肿大常被怀疑是原发性阑尾肿瘤,很难怀疑是转移性肿瘤,尤其是来自乳腺癌的转移。另一方面,包括乳腺癌激素治疗在内的药物治疗进展延长了患者生存期,有可能遇到以前很少见的转移病例。在此,我们报告一例在晚期乳腺癌激素治疗期间发现阑尾肿大,经腹腔镜切除并诊断为乳腺癌转移的病例。一名53岁女性经乳腺活检被诊断为浸润性导管癌(IDC),阑尾标本被诊断为浸润性小叶癌(ILC)。我们在此报告这一独特病例,并对之前的13篇报道进行详细综述。