比较 Aptima MG 和 Cobas TV/MG 检测泌尿生殖道和生殖道外样本中生殖支原体的结果。
Comparison of the Aptima MG and Cobas TV/MG tests for the detection of Mycoplasma genitalium in urogenital and extragenital samples.
机构信息
Servicio de Microbiología y Parasitología Clínica, Hospital de Valme, Sevilla, Spain.
Centro de Infecciones de Transmisión Sexual, Hospital Duques del Infantado, Sevilla, Spain.
出版信息
Enferm Infecc Microbiol Clin (Engl Ed). 2023 Feb;41(2):103-106. doi: 10.1016/j.eimce.2022.07.005. Epub 2022 Jul 26.
BACKGROUND
Mycoplasma genitalium (M. genitalium) is an emerging sexually transmitted pathogen of increasing importance. The objective of this study was to compare two tests for the detection of M. genitalium; the Aptima® MG test (Hologic® Inc., San Diego, CA) and the Cobas® TV/MG test (Roche® Diagnostics, Mannheim, Germany).
METHODS
This is a prospective descriptive study where a total of 489 genital and extragenital samples were analyzed in parallel and in random order by both systems. The samples were collected from patients attending the Sexually Transmitted Infections Center in Seville and the Infectious Diseases consultation of the Virgen de Valme Hospital.
RESULTS
The overall agreement between both trials was very good (k > 0.91). The sensitivity and specificity of the Aptima® MG test were 100% and 98.7% respectively for the Cobas® TV/MG test.
CONCLUSION
Both systems showed excellent performance for the detection of M. genitalium.
背景
生殖支原体（M. genitalium）是一种新兴的性传播病原体，其重要性日益增加。本研究的目的是比较两种检测生殖支原体的方法；Aptima® MG 检测（Hologic® Inc.，圣地亚哥，加利福尼亚州）和 Cobas® TV/MG 检测（罗氏诊断公司，曼海姆，德国）。
方法
这是一项前瞻性描述性研究，共有 489 例泌尿生殖道和非泌尿生殖道样本通过两种系统以平行和随机的方式进行了分析。样本来自塞维利亚性传播感染中心和瓦尔梅医院传染病咨询处的患者。
结果
两种试验之间的总体一致性非常好（k>0.91）。Aptima® MG 检测对 Cobas® TV/MG 检测的灵敏度和特异性分别为 100%和 98.7%。
结论
两种系统在检测生殖支原体方面均表现出优异的性能。
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