Department of Neurosurgery, The University of Arizona College of Medicine, Phoenix, AZ, United States.
Department of Orthopaedic & Sports Medicine, Harborview Medical Center, Seattle, WA, United States.
J Clin Neurosci. 2022 Sep;103:163-171. doi: 10.1016/j.jocn.2022.07.017. Epub 2022 Jul 27.
Burst fractures of the fifth lumbar vertebra (L5) are rare injuries and typically occur because of high-energy axial compressive load. Their unique anatomy and biomechanical characteristics distinguish them from other lumbar spine injuries. To the best of our knowledge, the treatment strategies for L5 burst fractures have not been thoroughly described. The aims of this case series and systematic review were to highlight the treatment strategies and outcomes of the L5 burst fractures.
We performed a retrospective case series of 8 patients treated for burst L5 fractures in our institution between 2005 and 2020. Additionally, a systematic review via PubMed and Cochrane Library databases according to PRISMA guidelines was performed to review L5 burst fractures treatment strategies. Only Articles in English with full text available were included. The references of the selected studies were checked to find all possible related articles. Treatment strategies were conservative, posterior segmental instrumentation and fixation (PSIF), PSIF with anterior corpectomy (AC), and PSIF with posterior corpectomy (PC). Outcomes measures included neurological status, radiological regional alignment, and complications.
A total of 1449 publications were found, and 29 articles were finally selected for analysis. Of those, 15 were retrospective case reports, and 14 were retrospective case series. One hundred and sixty-nine patients were found in the review. The author's eight cases were added to the found in the literature for a methodological quality assessment. There were 52 (29%) patients managed non-operative, and 125 (71%) underwent surgery. One-hundred-two patients were neurologically intact, of whom 46 were managed non-operative. Canal compromise in intact patients ranged between 20 and 90%. Posterior segmental fixation and instrumentation with decompression was the preferred surgical strategy in patients with neurological deficits. Patients with combined anterior column restoration and anterior approach showed vertebral height and lordosis restoration. A 79% of the operative treated group reported neurological improvement. Patients with pre-operative neurological deficit managed non-operative reported the highest rate of complications (33.3%).
In the setting of L5 burst fractures, neurological injuries have a promising prognosis after surgery and are not correlated with the degree of canal stenosis. The compromise of the L5 vertebra affects the sagittal balance and its restoration can be achieved with an anterior corpectomy. Nonoperative management can be considered in cases of reasonable alignment, and no neurologic deficit.
第五腰椎(L5)爆裂性骨折较为罕见,通常由高能轴向压缩负荷引起。其独特的解剖结构和生物力学特征使其与其他腰椎损伤区分开来。据我们所知,L5 爆裂性骨折的治疗策略尚未得到充分描述。本病例系列和系统回顾的目的是强调 L5 爆裂性骨折的治疗策略和结果。
我们对 2005 年至 2020 年期间在我院接受治疗的 8 例 L5 爆裂性骨折患者进行了回顾性病例系列研究。此外,我们还按照 PRISMA 指南通过 PubMed 和 Cochrane Library 数据库进行了系统回顾,以回顾 L5 爆裂性骨折的治疗策略。仅纳入全文可用的英文文章。所选研究的参考文献也进行了检查,以找到所有可能的相关文章。治疗策略包括保守治疗、后路节段性内固定和固定(PSIF)、PSIF 加前路椎体切除术(AC)和 PSIF 加后路椎体切除术(PC)。结局测量包括神经状态、影像学区域对齐和并发症。
共发现 1449 篇文献,最终有 29 篇文章被纳入分析。其中 15 篇为回顾性病例报告,14 篇为回顾性病例系列。在综述中发现 169 例患者。在文献中发现了作者的 8 例病例,以进行方法学质量评估。其中 52 例(29%)患者接受非手术治疗,125 例(71%)患者接受手术治疗。102 例患者神经功能完整,其中 46 例接受非手术治疗。神经功能完整患者的椎管狭窄程度在 20%至 90%之间。神经功能缺损患者首选后路节段性固定和减压的手术策略。同时进行前路柱体重建和前路入路的患者显示椎体高度和前凸恢复。手术治疗组 79%的患者报告神经功能改善。术前有神经功能缺损且接受非手术治疗的患者报告并发症发生率最高(33.3%)。
在 L5 爆裂性骨折的情况下,手术治疗后神经损伤具有良好的预后,与椎管狭窄程度无关。L5 椎体的破坏会影响矢状位平衡,通过前路椎体切除术可以恢复其平衡。对于具有合理对线且无神经功能缺损的患者,可以考虑非手术治疗。