Engineering Research Center for Biotechnology of Active Substances (Ministry of Education), Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing 401331, PR China.
Engineering Research Center for Biotechnology of Active Substances (Ministry of Education), Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing 401331, PR China.
Colloids Surf B Biointerfaces. 2022 Oct;218:112711. doi: 10.1016/j.colsurfb.2022.112711. Epub 2022 Jul 20.
Green tea is a popular beverage and is widely consumed due to its taste and antioxidative polyphenols. Herein, a smartphone-based colorimetric reader using cobalt oxyhydroxide (CoOOH) nanorings has been successfully applied to detect antioxidants in green tea with high reliability and robustness. By exploiting the oxidase-mimicking activity, the as-synthesized CoOOH nanorings replaces natural enzymes to directly catalyze oxidate colorless 3,3 ´ ,5,5 ´ -tetramethylbenzidine (TMB), while antioxidants can disintegrate CoOOH, leading to an antioxidant concentration-dependent color change. Benefiting from the CoOOH nanorings-based colorimetric strategy, a smartphone-assistant nanosensor was devised for portable and visual detection of antioxidants in green tea. The proposed method can be extended to visual detection of a diverse range of diseases by responding to their specific antioxidant, and thus provide a pivotal disease toolbox that is compatible for development at the point-of-care.
绿茶是一种受欢迎的饮料，因其口感和抗氧化多酚而被广泛饮用。在此，我们成功地应用了一种基于智能手机的比色读取器，该读取器使用钴氢氧化物 (CoOOH) 纳米环来检测绿茶中的抗氧化剂，具有高可靠性和鲁棒性。通过利用氧化酶模拟活性，所合成的 CoOOH 纳米环可替代天然酶直接催化无色 3,3´,5,5´-四甲基联苯胺 (TMB) 的氧化，而抗氧化剂可以分解 CoOOH，导致抗氧化剂浓度依赖性的颜色变化。得益于基于 CoOOH 纳米环的比色策略，我们设计了一种基于智能手机的纳米传感器，用于便携式和可视化检测绿茶中的抗氧化剂。该方法可以通过响应特定的抗氧化剂来扩展到对各种疾病的可视化检测，从而为即时护理开发提供了一个关键的疾病工具箱。
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