Department of Dermatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Clin Dermatol. 2022 Nov-Dec;40(6):728-742. doi: 10.1016/j.clindermatol.2022.07.007. Epub 2022 Jul 28.
Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive dermatosis characterized by a nonscarring papulosquamous eruption and specific antibodies in the patient's serum. Genetic and environmental factors represent the leading causes of SCLE; however, several case reports in the literature link SCLE to various types of cancer. This review assesses the association between SCLE and neoplastic disorders. A PubMed search was performed for all relevant publications on cancer-associated SCLE from 1982 to 2022. This review supports the hypothesis that SCLE should be considered a facultative paraneoplastic phenomenon. It also emphasizes the importance of cancer screening in patients presenting SCLE manifestations.
亚急性皮肤型狼疮（SCLE）是一种光敏感的皮肤病，其特征为非瘢痕性丘疹鳞屑疹和患者血清中的特异性抗体。遗传和环境因素是 SCLE 的主要病因；然而，文献中的几例病例报告将 SCLE 与各种类型的癌症联系起来。这篇综述评估了 SCLE 与肿瘤性疾病之间的关联。对从 1982 年到 2022 年发表的所有与癌症相关的 SCLE 的相关出版物进行了 PubMed 检索。这篇综述支持了这样一种假说，即 SCLE 应被视为一种兼性副肿瘤现象。它还强调了在出现 SCLE 表现的患者中进行癌症筛查的重要性。
