de Araújo Lucas Peixoto, da Rosa Wellington Luiz de Oliveira, Gobbo Leandro Bueno, da Silva Tamares Andrade, de Almeida José Flávio Affonso, Ferraz Caio Cezar Randi
Department of Restorative Dentistry, Division of Endodontics, Piracicaba Dental School, State University of Campinas (UNICAMP), Avenue Limeira 901, Piracicaba, SP 13144-018, Brazil.
Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas (UFPEL), Pelotas, RS, Brazil.
Photodiagnosis Photodyn Ther. 2022 Dec;40:103039. doi: 10.1016/j.pdpdt.2022.103039. Epub 2022 Jul 28.
Photodynamic therapy (PDT) is an adjunctive treatment that aims to inactivate microorganisms through an oxidative reaction produced by irradiating a photosensitizing agent. The quest for improved root canal disinfection has sought supplementary methods when performing chemomechanical procedures. From this perspective, PDT protocols were proposed as an auxiliary approach in endodontics. Thus, the aim of this study was to investigate publication metrics and research trends related to this scope.
This review is reported in accordance with the PRISMA 2020 recommendations. Two blinded and independent reviewers systematically searched five electronic databases until December 2021. The acquired bibliometric parameters were analyzed through descriptive statistics and graphical mappings with VOSViewer software.
The search retrieved 342 studies from 84 journals originating from 33 countries. About 85% of the included studies were published over the last decade. Most of the available evidence is laboratory-based (74.5%), and the main clinical outcomes evaluated were microbiological load reduction and postoperative pain. Mayram Pourhajibagher is the researcher with the most publications as the first author (n = 16). Tehran University of Medical Sciences carried out the highest number of studies (n = 29), and Photodiagnosis and Photodynamic Therapy is the journal that most published on the theme (n = 111).
This bibliometric analysis mapped and discussed the scientific progress and publication metrics in PDT in endodontic research. Additionally, future perspectives were highlighted and should focus on discovering new photosensitizer agents, standardizing optimal photoactivation protocols, and conducting more clinical-oriented research.
光动力疗法（PDT）是一种辅助治疗方法，旨在通过照射光敏剂产生的氧化反应使微生物失活。在进行化学机械操作时，为寻求更好的根管消毒方法，人们一直在寻找补充方法。从这个角度来看，光动力疗法方案被提议作为牙髓病学中的一种辅助方法。因此，本研究的目的是调查与该领域相关的发表指标和研究趋势。
本综述按照PRISMA 2020建议进行报告。两名盲法且独立的评审员系统地检索了五个电子数据库，直至2021年12月。通过描述性统计和使用VOSViewer软件的图形映射对获取的文献计量参数进行分析。
检索共得到来自33个国家84种期刊的342项研究。纳入研究中约85%是在过去十年发表的。大多数现有证据基于实验室研究（74.5%），评估的主要临床结果是微生物负荷降低和术后疼痛。迈拉姆·普尔哈吉巴agher是作为第一作者发表论文最多的研究者（n = 16）。德黑兰医科大学开展的研究数量最多（n = 29），《光诊断与光动力疗法》是发表该主题文章最多的期刊（n = 111）。
本文献计量分析描绘并讨论了牙髓病学研究中光动力疗法的科学进展和发表指标。此外，还强调了未来的研究方向，应侧重于发现新的光敏剂、规范最佳光激活方案以及开展更多以临床为导向的研究。
