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[心血管疾病患者随访干预研究中死亡患者与存活患者的比较生化参数]

[Comparative biochemical parameters in deceased and living patients in a follow-up intervention study of cardiovascular patients].

作者信息

Gerhard W, Hempel W E, Richter K, Vogelreuter K, Wagenknecht C U

出版信息

Z Alternsforsch. 1987 Mar-Apr;42(2):101-10.

PMID:3590837
Abstract

After the laboratory-diagnostical spectrum had been analysed by means of a representative check of probationer with a state suspected of heart and vessel diseases on the screen of the X-ray mass examination in longitudinal section and cross-section with derived conclusions the results had been checked by means of comparison with the dead and not dead of this population in the follow up. The parameter sedimentation rate of erythrocyte, blood sugar, the enzymes "ASAT" and "ALAT" and total cholesterol with stronger pronounced proneness could substantiate the causal connection to this population of persons suffering from a heart disease as well. Hence followed derived relations to the severe degree of heart and vessel disease and beside this to the prognostical estimation of the disease for the parameter uric acid, hemoglobin/hematocrit and creatinine in the serum. The number of leucocytes, the serum protein, the separation of fractions of serum protein and lability test of serum by electrophoresis did not result in any findings, which allowed any connection with heart and vessel diseases, also concerning the persons who died in the course of the study, so that the demand for a differentiated, well-aimed differential-diagnostical use of these expensive research methods also for this extreme situation is substantiated once more. The results are discussed in comparison as well as in connection with the results found out of the total check and in dependence of age and sexes.

摘要

在通过对疑似患有心脏和血管疾病的受检者进行代表性检查,在X射线大规模检查的纵向和横向屏幕上进行分析并得出结论后,通过与该人群中死亡和未死亡者的随访结果进行比较,对实验室诊断谱进行了核查。红细胞沉降率、血糖、“ASAT”和“ALAT”酶以及总胆固醇等参数具有更强的明显倾向,也能够证实与该心脏病患者群体之间的因果关系。因此,得出了与心脏和血管疾病严重程度的派生关系,除此之外,还得出了血清中尿酸、血红蛋白/血细胞比容和肌酐等参数对疾病的预后估计。白细胞数量、血清蛋白、血清蛋白各组分的分离以及血清电泳稳定性试验均未得出任何能与心脏和血管疾病建立联系的结果,即使对于在研究过程中死亡的人也是如此,从而再次证实了即使在这种极端情况下,也需要对这些昂贵的研究方法进行有区别、有针对性的鉴别诊断应用。还对结果进行了比较讨论,并结合总体检查结果以及年龄和性别的依赖性进行了讨论。

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