味觉丧失作为吉兰-巴雷综合征“面瘫和感觉异常”变异型的首发症状。
Loss of Taste as an Initial Symptom of a "Facial Diplegia and Paresthesia" Variant of Guillain-Barré Syndrome.
机构信息
Department of Neurology, Chiba Rosai Hospital, Japan.
Department of Neurology, Graduate School of Medicine, Chiba University, Japan.
出版信息
Intern Med. 2022 Oct 1;61(19):2957-2959. doi: 10.2169/internalmedicine.9781-22. Epub 2022 Jul 29.
Abstract
Loss of taste is a relatively common symptom of coronavirus disease 2019 (COVID-19) and has also been considered a rare Guillain-Barré syndrome (GBS) symptom. We herein report a case of a facial diplegia and paresthesia (FDP) variant of GBS that initially presented as a loss of taste occurring two weeks after COVID-19 mRNA vaccination. The patient recovered completely after intravenous immunoglobulin therapy. Clinicians should consider the possibility of post-vaccination FDP manifesting as facial palsy and should be aware that GBS, including the FDP variant, can initially present as an isolated loss of taste.
摘要
失去味觉是 2019 冠状病毒病（COVID-19）的一个相对常见症状，也被认为是吉兰-巴雷综合征（GBS）的罕见症状。我们在此报告一例 FDP 变异型 GBS，最初表现为 COVID-19 mRNA 疫苗接种后两周出现味觉丧失。患者经静脉注射免疫球蛋白治疗后完全康复。临床医生应考虑 FDP 在接种疫苗后表现为面瘫的可能性，并应意识到包括 FDP 变异型在内的 GBS 最初可能表现为孤立性味觉丧失。
相似文献
1
Loss of Taste as an Initial Symptom of a "Facial Diplegia and Paresthesia" Variant of Guillain-Barré Syndrome.味觉丧失作为吉兰-巴雷综合征“面瘫和感觉异常”变异型的首发症状。
Intern Med. 2022 Oct 1;61(19):2957-2959. doi: 10.2169/internalmedicine.9781-22. Epub 2022 Jul 29.
2
Guillain-Barré Syndrome: A Variant Consisting of Facial Diplegia and Paresthesia with Left Facial Hemiplegia Associated with Antibodies to Galactocerebroside and Phosphatidic Acid.吉兰-巴雷综合征：一种由双侧面瘫、感觉异常伴左侧面部偏瘫组成的变异型，与抗半乳糖脑苷脂和磷脂酸抗体相关。
Am J Case Rep. 2017 Oct 2;18:1048-1052. doi: 10.12659/ajcr.904925.
3
A 44-Year-Old Hispanic Man with Loss of Taste and Bilateral Facial Weakness Diagnosed with Guillain-Barré Syndrome and Bell's Palsy Associated with SARS-CoV-2 Infection Treated with Intravenous Immunoglobulin.一名44岁的西班牙裔男性，味觉丧失且双侧面部无力，被诊断为吉兰-巴雷综合征和贝尔麻痹，与SARS-CoV-2感染相关，接受静脉注射免疫球蛋白治疗。
Am J Case Rep. 2020 Oct 31;21:e927956. doi: 10.12659/AJCR.927956.
4
[Isolated facial diplegia as an atypical variant of Guillain-Barre syndrome after suspected SARS-CoV-2 infection].[疑似新型冠状病毒感染后孤立性面瘫作为吉兰-巴雷综合征的非典型变体]
Rev Fac Cien Med Univ Nac Cordoba. 2021 Dec 28;78(4):405-407. doi: 10.31053/1853.0605.v78.n4.32392.
5
Guillain-Barré Syndrome Presenting as Facial Diplegia after COVID-19 Vaccination: A Case Report.新冠病毒疫苗接种后出现面瘫的格林-巴利综合征：病例报告。
J Emerg Med. 2021 Dec;61(6):e141-e145. doi: 10.1016/j.jemermed.2021.07.062. Epub 2021 Aug 7.
6
Guillain-Barré syndrome variant with facial diplegia and paresthesias associated with IgM anti-GalNAc-GD1a antibodies.伴有双侧面瘫和感觉异常的格林-巴利综合征变异型，与IgM抗GalNAc-GD1a抗体相关。
Intern Med. 2015;54(3):345-7. doi: 10.2169/internalmedicine.54.2972.
7
Guillain-Barré syndrome variant with prominent facial diplegia, limb paresthesia, and brisk reflexes.伴有明显双侧面瘫、肢体感觉异常及腱反射亢进的吉兰-巴雷综合征变异型
J Neurol. 2012 Feb;259(2):370-1. doi: 10.1007/s00415-011-6169-8. Epub 2011 Jul 19.
8
[A variant of Guillain-Barré syndrome with prominent bilateral peripheral facial nerve palsy--facial diplegia and paresthesias].一种伴有显著双侧周围性面神经麻痹（面肌双瘫和感觉异常）的吉兰-巴雷综合征变体
Rinsho Shinkeigaku. 2004 Aug;44(8):549-52.
9
Sensory Ataxic Guillain-Barré Syndrome with Dysgeusia after mRNA COVID-19 Vaccination.mRNA COVID-19 疫苗接种后出现感觉运动性共济失调型吉兰-巴雷综合征伴味觉障碍
Intern Med. 2022 Jun 1;61(11):1757-1760. doi: 10.2169/internalmedicine.8967-21. Epub 2022 Mar 26.
10
Miller-Fisher syndrome and Guillain-Barre syndrome overlap syndrome following inactivated COVID-19 vaccine: Case report and scope review.接种灭活 COVID-19 疫苗后出现 Miller-Fisher 综合征与 Guillain-Barre 综合征重叠综合征：病例报告和范围综述。
Hum Vaccin Immunother. 2022 Nov 30;18(6):2125753. doi: 10.1080/21645515.2022.2125753. Epub 2022 Oct 31.
本文引用的文献
1
Adenovirus COVID-19 Vaccines and Guillain-Barré Syndrome with Facial Paralysis.腺病毒 COVID-19 疫苗与伴有面瘫的吉兰-巴雷综合征
Ann Neurol. 2022 Jan;91(1):162-163. doi: 10.1002/ana.26258. Epub 2021 Nov 12.
2
Guillain-Barré Syndrome Associated with COVID-19 Vaccination.与 COVID-19 疫苗接种相关的格林-巴利综合征。
Emerg Infect Dis. 2021 Dec;27(12):3175-3178. doi: 10.3201/eid2712.211634. Epub 2021 Oct 14.
3
COVID-19: Post-vaccine Smell and Taste Disorders: Report of 6 Cases.新冠病毒病：疫苗接种后嗅觉和味觉障碍：6例报告
Ear Nose Throat J. 2024 Feb;103(2):NP104-NP107. doi: 10.1177/01455613211033125. Epub 2021 Sep 1.
4
Bell's palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study.接种 mRNA（BNT162b2）和灭活（科兴）SARS-CoV-2 疫苗后出现贝尔麻痹：病例系列和巢式病例对照研究。
Lancet Infect Dis. 2022 Jan;22(1):64-72. doi: 10.1016/S1473-3099(21)00451-5. Epub 2021 Aug 16.
5
Bilateral facial weakness with paraesthesia variant of Guillain-Barré syndrome following Vaxzevria COVID-19 vaccine.接种Vaxzevria新冠疫苗后出现伴有感觉异常的吉兰-巴雷综合征双侧面部无力
J Neurol Neurosurg Psychiatry. 2022 Mar;93(3):341-342. doi: 10.1136/jnnp-2021-327027. Epub 2021 Jul 14.
6
Guillain-Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination.接种 SARS-CoV-2 疫苗后出现的格林-巴利综合征变异型。
Ann Neurol. 2021 Aug;90(2):315-318. doi: 10.1002/ana.26144. Epub 2021 Jul 2.
7
Guillain-Barré syndrome associated with SARS-CoV-2 infection: A systematic review and individual participant data meta-analysis.与 SARS-CoV-2 感染相关的吉兰-巴雷综合征：系统评价和个体参与者数据荟萃分析。
J Peripher Nerv Syst. 2020 Dec;25(4):335-343. doi: 10.1111/jns.12419. Epub 2020 Nov 5.
8
Neurological associations of COVID-19.新型冠状病毒肺炎的神经系统相关表现。
Lancet Neurol. 2020 Sep;19(9):767-783. doi: 10.1016/S1474-4422(20)30221-0. Epub 2020 Jul 2.
9
Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study.嗅觉和味觉障碍作为冠状病毒病（COVID-19）轻至中度形式的临床特征：一项多中心欧洲研究。
Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2251-2261. doi: 10.1007/s00405-020-05965-1. Epub 2020 Apr 6.
10
Clinical classification of 103 Japanese patients with Guillain-Barré syndrome.103例日本格林-巴利综合征患者的临床分类
J Neurol Sci. 2016 Oct 15;369:43-47. doi: 10.1016/j.jns.2016.08.002. Epub 2016 Aug 2.
Zotero 插件