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味觉丧失作为吉兰-巴雷综合征“面瘫和感觉异常”变异型的首发症状。

Loss of Taste as an Initial Symptom of a "Facial Diplegia and Paresthesia" Variant of Guillain-Barré Syndrome.

机构信息

Department of Neurology, Chiba Rosai Hospital, Japan.

Department of Neurology, Graduate School of Medicine, Chiba University, Japan.

出版信息

Intern Med. 2022 Oct 1;61(19):2957-2959. doi: 10.2169/internalmedicine.9781-22. Epub 2022 Jul 29.

DOI:10.2169/internalmedicine.9781-22
PMID:35908975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9593143/
Abstract

Loss of taste is a relatively common symptom of coronavirus disease 2019 (COVID-19) and has also been considered a rare Guillain-Barré syndrome (GBS) symptom. We herein report a case of a facial diplegia and paresthesia (FDP) variant of GBS that initially presented as a loss of taste occurring two weeks after COVID-19 mRNA vaccination. The patient recovered completely after intravenous immunoglobulin therapy. Clinicians should consider the possibility of post-vaccination FDP manifesting as facial palsy and should be aware that GBS, including the FDP variant, can initially present as an isolated loss of taste.

摘要

失去味觉是 2019 冠状病毒病(COVID-19)的一个相对常见症状,也被认为是吉兰-巴雷综合征(GBS)的罕见症状。我们在此报告一例 FDP 变异型 GBS,最初表现为 COVID-19 mRNA 疫苗接种后两周出现味觉丧失。患者经静脉注射免疫球蛋白治疗后完全康复。临床医生应考虑 FDP 在接种疫苗后表现为面瘫的可能性,并应意识到包括 FDP 变异型在内的 GBS 最初可能表现为孤立性味觉丧失。

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本文引用的文献

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Adenovirus COVID-19 Vaccines and Guillain-Barré Syndrome with Facial Paralysis.腺病毒 COVID-19 疫苗与伴有面瘫的吉兰-巴雷综合征
Ann Neurol. 2022 Jan;91(1):162-163. doi: 10.1002/ana.26258. Epub 2021 Nov 12.
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Guillain-​Barré Syndrome Associated with COVID-19 Vaccination.与 COVID-19 疫苗接种相关的格林-巴利综合征。
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Guillain-Barré syndrome associated with SARS-CoV-2 infection: A systematic review and individual participant data meta-analysis.与 SARS-CoV-2 感染相关的吉兰-巴雷综合征:系统评价和个体参与者数据荟萃分析。
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